PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCES
The article presents the results of studies of metabolic indicators of oral liquid in patients with a wide range of somatic illnesses that reflecting the functional state of the prooxidant-antioxidant system. During the studies established that most increase in activity of oxidation processes in the...
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| Format: | Article |
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Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”
2016-08-01
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| Serier: | Кубанский научный медицинский вестник |
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| Online adgang: | https://ksma.elpub.ru/jour/article/view/547 |
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| author | I. M. Bykov E. A. Alekseenko K. A. Popov N. I. Bykova A. A. Ovsyannikova I. A. Egorova E. E. Esaulenko T. V. Eremina |
| author_facet | I. M. Bykov E. A. Alekseenko K. A. Popov N. I. Bykova A. A. Ovsyannikova I. A. Egorova E. E. Esaulenko T. V. Eremina |
| author_sort | I. M. Bykov |
| collection | DOAJ |
| description | The article presents the results of studies of metabolic indicators of oral liquid in patients with a wide range of somatic illnesses that reflecting the functional state of the prooxidant-antioxidant system. During the studies established that most increase in activity of oxidation processes in the background of decrease in activity of all enzymes of antiradical protection was observed in patients with diabetes mellitus type 2. Also a significant increase in FRO was observed in patients with chronic obstructive pulmonary disease, while they have identified imbalance in the functioning of enzyme systems and the highest amplitude changes in the activity of enzymes of antiradical protection. We also established the activation of free radical processes in patients of other groups, but less pronounced on the background of a minor changes in the activity of enzymes. The obtained data demonstrate the development of oxidative stress at the local level in the oral fluid which is probably a reflection of the systemic metabolic changes under examined somatic pathologies and presents prospect of studying oral fluid in the laboratory diagnosis of oxidative metabolism disorders. |
| format | Article |
| id | doaj-art-b70d4e0b8b9542caa5cfee82587fceee |
| institution | Matheson Library |
| issn | 1608-6228 2541-9544 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” |
| record_format | Article |
| series | Кубанский научный медицинский вестник |
| spelling | doaj-art-b70d4e0b8b9542caa5cfee82587fceee2025-08-04T13:05:09ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442016-08-0141620547PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCESI. M. Bykov0E. A. Alekseenko1K. A. Popov2N. I. Bykova3A. A. Ovsyannikova4I. A. Egorova5E. E. Esaulenko6T. V. Eremina7ФГБОУ ВО КубГМУ Минздрава РоссииФГБОУ ВО КубГМУ Минздрава РоссииФГБОУ ВО КубГМУ Минздрава РоссииФГБОУ ВО КубГМУ Минздрава РоссииФГБОУ ВО КубГМУ Минздрава РоссииФГБОУ ВО КубГМУ Минздрава РоссииФГБОУ ВО КубГМУ Минздрава РоссииФГБОУ ВО КубГМУ Минздрава РоссииThe article presents the results of studies of metabolic indicators of oral liquid in patients with a wide range of somatic illnesses that reflecting the functional state of the prooxidant-antioxidant system. During the studies established that most increase in activity of oxidation processes in the background of decrease in activity of all enzymes of antiradical protection was observed in patients with diabetes mellitus type 2. Also a significant increase in FRO was observed in patients with chronic obstructive pulmonary disease, while they have identified imbalance in the functioning of enzyme systems and the highest amplitude changes in the activity of enzymes of antiradical protection. We also established the activation of free radical processes in patients of other groups, but less pronounced on the background of a minor changes in the activity of enzymes. The obtained data demonstrate the development of oxidative stress at the local level in the oral fluid which is probably a reflection of the systemic metabolic changes under examined somatic pathologies and presents prospect of studying oral fluid in the laboratory diagnosis of oxidative metabolism disorders.https://ksma.elpub.ru/jour/article/view/547ротовая жидкостьантиоксидантная системаокислительный стрессoral fluidantioxidant systemoxidative stress |
| spellingShingle | I. M. Bykov E. A. Alekseenko K. A. Popov N. I. Bykova A. A. Ovsyannikova I. A. Egorova E. E. Esaulenko T. V. Eremina PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCES Кубанский научный медицинский вестник ротовая жидкость антиоксидантная система окислительный стресс oral fluid antioxidant system oxidative stress |
| title | PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCES |
| title_full | PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCES |
| title_fullStr | PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCES |
| title_full_unstemmed | PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCES |
| title_short | PROSPECTS OF STUDYING OF ORAL LIQUID IN LABORATORY DIAGNOSTICS OF OXIDATIVE METABOLISM DISTURBANCES |
| title_sort | prospects of studying of oral liquid in laboratory diagnostics of oxidative metabolism disturbances |
| topic | ротовая жидкость антиоксидантная система окислительный стресс oral fluid antioxidant system oxidative stress |
| url | https://ksma.elpub.ru/jour/article/view/547 |
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