Influence of Tariquidar, an ABC Transporter Inhibitor, on the Ca<sup>2+</sup>-Dependent Mitochondrial Permeability Transition Pore
<b>Background</b>: Tariquidar (Tq) is an inhibitor of the multidrug resistance (MDR) proteins relevant to ATP-binding cassette transporters (ABC transporters), which suppresses the ATP-dependent efflux of a variety of hydrophilic and amphipathic compounds, including anticancer drugs. Tq...
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Main Authors: | Tatiana A. Fedotcheva, Alexey G. Kruglov, Nadezhda I. Fedotcheva |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-06-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/18/6/924 |
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