Spike Timing-Dependent Plasticity and Random Inputs Shape Interspike Interval Regularity of Model STN Neurons

Spike Timing-Dependent Plasticity and Random Inputs Shape Interspike Interval Regularity of Model STN Neurons

<b>Background/Objectives:</b> Neuronal oscillations play a key role in the symptoms of Parkinson’s disease (PD). This study investigates the effects of random synaptic inputs, their correlations, and the interaction with synaptic dynamics and spike timing-dependent plasticity (STDP) on t...

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Bibliographic Details
Main Authors: Thoa Thieu, Roderick Melnik
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomedicines
Subjects:
activity-dependent development of nervous systems
spike timing-dependent plasticity
coupled models in medical applications
neuromorphic systems
neurodegenerative diseases
enhanced Hodgkin–Huxley models
Online Access:https://www.mdpi.com/2227-9059/13/7/1718
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