Pemphigus Herpetiformis in Childhood: Clinical Case

Background. Pemphigus herpetiformis is a rare atypical bullous dermatosis of autoimmune nature. It is characterized by rashes in the form of plaques with papules and vesicles at peripheral areas, or in the form of grouped papules, vesicles or tense bubbles with clinical similarity to During's h...

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Main Authors: Nikolay N. Murashkin, Alexander I. Materikin, Roman V. Epishev, Maria A. Leonova, Leonid A. Opryatin, Dmitri V. Fedorov, Roman A. Ivanov, Alena A. Savelova, Oksana R. Katunina, Kirill A. Kulikov, Ilgiz I. Yarullin
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2023-11-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/3308
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author Nikolay N. Murashkin
Alexander I. Materikin
Roman V. Epishev
Maria A. Leonova
Leonid A. Opryatin
Dmitri V. Fedorov
Roman A. Ivanov
Alena A. Savelova
Oksana R. Katunina
Kirill A. Kulikov
Ilgiz I. Yarullin
author_facet Nikolay N. Murashkin
Alexander I. Materikin
Roman V. Epishev
Maria A. Leonova
Leonid A. Opryatin
Dmitri V. Fedorov
Roman A. Ivanov
Alena A. Savelova
Oksana R. Katunina
Kirill A. Kulikov
Ilgiz I. Yarullin
author_sort Nikolay N. Murashkin
collection DOAJ
description Background. Pemphigus herpetiformis is a rare atypical bullous dermatosis of autoimmune nature. It is characterized by rashes in the form of plaques with papules and vesicles at peripheral areas, or in the form of grouped papules, vesicles or tense bubbles with clinical similarity to During's herpetiformis dermatitis. Pemphigus herpetiformis diagnosis in pediatric practice is difficult due to the similarity of clinical manifestations to bullous dermatoses of other etiology, the rarity of the disease in children, and small number of scientific publications.Clinical case description. Clinical case of pemphigus herpetiformis in a child is described. All necessary diagnostic algorithms for diagnosis and therapeutic tactics for patient management are presented. Dapsone and prednisolone were used as first-line drugs during the patient's treatment. They have shown its efficacy in management of such patients.Conclusion. Differential diagnosis of pemphigus herpetiformis and other bullous dermatoses in children is presented. The results of successful drug treatment are shown.
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spelling doaj-art-b31d8a28eaa44b8eaada84cb381ddcbc2025-08-04T13:09:42Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352023-11-0122545846310.15690/vsp.v22i5.26362131Pemphigus Herpetiformis in Childhood: Clinical CaseNikolay N. Murashkin0Alexander I. Materikin1Roman V. Epishev2Maria A. Leonova3Leonid A. Opryatin4Dmitri V. Fedorov5Roman A. Ivanov6Alena A. Savelova7Oksana R. Katunina8Kirill A. Kulikov9Ilgiz I. Yarullin10National Medical Research Center of Children’s Health; Sechenov First Moscow State Medical University; Central State Medical Academy of Department of Presidential AffairsNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthNational Medical Research Center of Children’s HealthCentral State Medical Academy of Department of Presidential AffairsBackground. Pemphigus herpetiformis is a rare atypical bullous dermatosis of autoimmune nature. It is characterized by rashes in the form of plaques with papules and vesicles at peripheral areas, or in the form of grouped papules, vesicles or tense bubbles with clinical similarity to During's herpetiformis dermatitis. Pemphigus herpetiformis diagnosis in pediatric practice is difficult due to the similarity of clinical manifestations to bullous dermatoses of other etiology, the rarity of the disease in children, and small number of scientific publications.Clinical case description. Clinical case of pemphigus herpetiformis in a child is described. All necessary diagnostic algorithms for diagnosis and therapeutic tactics for patient management are presented. Dapsone and prednisolone were used as first-line drugs during the patient's treatment. They have shown its efficacy in management of such patients.Conclusion. Differential diagnosis of pemphigus herpetiformis and other bullous dermatoses in children is presented. The results of successful drug treatment are shown.https://vsp.spr-journal.ru/jour/article/view/3308pemphigus herpetiformisdiagnosisindirect immunofluorescence testtreatmentdapsoneprednisolonechildrenbullous dermatosis
spellingShingle Nikolay N. Murashkin
Alexander I. Materikin
Roman V. Epishev
Maria A. Leonova
Leonid A. Opryatin
Dmitri V. Fedorov
Roman A. Ivanov
Alena A. Savelova
Oksana R. Katunina
Kirill A. Kulikov
Ilgiz I. Yarullin
Pemphigus Herpetiformis in Childhood: Clinical Case
Вопросы современной педиатрии
pemphigus herpetiformis
diagnosis
indirect immunofluorescence test
treatment
dapsone
prednisolone
children
bullous dermatosis
title Pemphigus Herpetiformis in Childhood: Clinical Case
title_full Pemphigus Herpetiformis in Childhood: Clinical Case
title_fullStr Pemphigus Herpetiformis in Childhood: Clinical Case
title_full_unstemmed Pemphigus Herpetiformis in Childhood: Clinical Case
title_short Pemphigus Herpetiformis in Childhood: Clinical Case
title_sort pemphigus herpetiformis in childhood clinical case
topic pemphigus herpetiformis
diagnosis
indirect immunofluorescence test
treatment
dapsone
prednisolone
children
bullous dermatosis
url https://vsp.spr-journal.ru/jour/article/view/3308
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