OrgaCCC: Orthogonal graph autoencoders for constructing cell-cell communication networks on spatial transcriptomics data.
Cell-cell communication (CCC) is a fundamental biological process essential for maintaining the functionality of multicellular organisms. It allows cells to coordinate their activities, sustain tissue homeostasis, and adapt to environmental changes. However, understanding the mechanisms underlying i...
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Main Authors: | Xixuan Feng, Shuqin Zhang, Limin Li |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-06-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1013212 |
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