ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS
A history case of systemic juvenile idiopathic arthritis with early onset and severe clinical case, resistant to treatment with standard immunosuppressive agents is represented in the article. This case demonstrates high clinical efficacy of adalimumab in a patient with severe course of systemic juv...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2013-12-01
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| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/269 |
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| author | R. V. Denisova E. I. Alexeeva K. B. Isaeva T. V. Sleptsova T. M. Bzarova S. I. Valieva E. V. Mitenko E. G. Chistyakova A. M. Chomakhidze A. N. Fetisova O. L. Lomakina |
| author_facet | R. V. Denisova E. I. Alexeeva K. B. Isaeva T. V. Sleptsova T. M. Bzarova S. I. Valieva E. V. Mitenko E. G. Chistyakova A. M. Chomakhidze A. N. Fetisova O. L. Lomakina |
| author_sort | R. V. Denisova |
| collection | DOAJ |
| description | A history case of systemic juvenile idiopathic arthritis with early onset and severe clinical case, resistant to treatment with standard immunosuppressive agents is represented in the article. This case demonstrates high clinical efficacy of adalimumab in a patient with severe course of systemic juvenile idiopathic arthritis, prolonged remission of extra-articular involvement and persistent polyarthritis. By the 4th week of the treatment inflammatory changes in the joints had arrested, range of motions had widened, laboratory markers of activity had normalized and non-active stage of the disease had been established. The duration of the remission of articular syndrome was 2 years, no relapses were observed during the follow-up period. |
| format | Article |
| id | doaj-art-b22eb9e7007a4b1d8e0c20f5a0bca06b |
| institution | Matheson Library |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2013-12-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-b22eb9e7007a4b1d8e0c20f5a0bca06b2025-08-04T13:09:29Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352013-12-0112612312910.15690/vsp.v12i6.887269ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITISR. V. Denisova0E. I. Alexeeva1K. B. Isaeva2T. V. Sleptsova3T. M. Bzarova4S. I. Valieva5E. V. Mitenko6E. G. Chistyakova7A. M. Chomakhidze8A. N. Fetisova9O. L. Lomakina10Scientific Centre of Children Health of RAMS, MoscowScientific Centre of Children Health of RAMS, Moscow; I.M. Sechenov First Moscow State Medical University,Scientific Centre of Children Health of RAMS, MoscowScientific Centre of Children Health of RAMS, MoscowScientific Centre of Children Health of RAMS, MoscowScientific Centre of Children Health of RAMS, Moscow,Scientific Centre of Children Health of RAMS, MoscowScientific Centre of Children Health of RAMS, Moscow; I.M. Sechenov First Moscow State Medical UniversityScientific Centre of Children Health of RAMS, MoscowScientific Centre of Children Health of RAMS, MoscowScientific Centre of Children Health of RAMS, MoscowA history case of systemic juvenile idiopathic arthritis with early onset and severe clinical case, resistant to treatment with standard immunosuppressive agents is represented in the article. This case demonstrates high clinical efficacy of adalimumab in a patient with severe course of systemic juvenile idiopathic arthritis, prolonged remission of extra-articular involvement and persistent polyarthritis. By the 4th week of the treatment inflammatory changes in the joints had arrested, range of motions had widened, laboratory markers of activity had normalized and non-active stage of the disease had been established. The duration of the remission of articular syndrome was 2 years, no relapses were observed during the follow-up period.https://vsp.spr-journal.ru/jour/article/view/269childrensystemic juvenile idiopathic arthritisadalimumab |
| spellingShingle | R. V. Denisova E. I. Alexeeva K. B. Isaeva T. V. Sleptsova T. M. Bzarova S. I. Valieva E. V. Mitenko E. G. Chistyakova A. M. Chomakhidze A. N. Fetisova O. L. Lomakina ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS Вопросы современной педиатрии children systemic juvenile idiopathic arthritis adalimumab |
| title | ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS |
| title_full | ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS |
| title_fullStr | ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS |
| title_full_unstemmed | ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS |
| title_short | ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS |
| title_sort | adalimumab in treatment of systemic juvenile idiopathic arthritis |
| topic | children systemic juvenile idiopathic arthritis adalimumab |
| url | https://vsp.spr-journal.ru/jour/article/view/269 |
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