Simultaneous determination of related substances of oxytetracycline in pharmaceutical semi-solid form by HPLC method
Simultaneous determination of oxytetracycline, 4-epioxytetracycline, alpha-apooxytetracycline, tetracycline, beta-apooxytetracycline on C18 columns has been accomplished using a high performance liquid chromatographic method with UV detection. Separation was achieved on a Hypersil BDS RP-C18 column...
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| Format: | Article |
| Language: | English |
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Asociaţia Naţională a Fabricanţilor de Produse de Uz Veterinar
2013-05-01
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| Series: | Medicamentul Veterinar |
| Subjects: | |
| Online Access: | http://www.veterinarypharmacon.com/docs/1203-2013-14-1-ART-4.eng.pdf |
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| Summary: | Simultaneous determination of oxytetracycline, 4-epioxytetracycline, alpha-apooxytetracycline, tetracycline, beta-apooxytetracycline on C18 columns has been accomplished using a high performance liquid chromatographic method with UV detection. Separation was achieved on a Hypersil BDS RP-C18 column with a mobile phase consisted of acetonitrile-methanol-80 mM dipotassium phosphate pH 7,5 at a flow rate of 0,7 mL min-1. Absorbance measurements were held at 254 nm. |
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| ISSN: | 1843-9527 2069-2463 |