Production of bioactive cytokines using plant expression system for cardiovascular cell differentiation from human pluripotent stem cells

Production of bioactive cytokines using plant expression system for cardiovascular cell differentiation from human pluripotent stem cells

Abstract Bioactive cytokines such as vascular endothelial growth factor (VEGF) and Activin A are critical for the differentiation of stem cells into vascular endothelial cells and cardiomyocytes. However, production of the cytokines using conventional Escherichia coli or mammalian cell expression sy...

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Bibliographic Details
Main Authors: Kozue Murata, Kanae Takamura, Risa Watanabe, Akitomo Nagashima, Miho Miyauchi, Yoshiteru Miyauchi, Hidetoshi Masumoto
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Stem Cell Research & Therapy
Subjects:
Vascular endothelial growth factor (VEGF)
Activin A
Cardiomyocyte
Endothelial cell
Induced pluripotent stem cell (iPS cell) (iPSC)
Online Access:https://doi.org/10.1186/s13287-025-04424-0
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