Analysis of original bis-arylazaazkanes derivatives compliance with the calculated pharmacophoric models of biaromatic ligands of cardioprotective drugs biotargets
Eight important biotargets of biaromatic cardioprotective drugs were selected in this work: calcium Cav1.2-channel, sodium Nav1.5-channel, potassium hERG-channel and Kv1.5-channel, HCN-channel, β1-adrenergic receptor, ryanodine RyR2-receptor and σ1-receptor. Biaromatic ligands databases were collect...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
LLC “Publisher OKI”
2024-06-01
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Series: | Фармакокинетика и Фармакодинамика |
Subjects: | |
Online Access: | https://www.pharmacokinetica.ru/jour/article/view/410 |
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