Identification of glycosylated flavonoids as new physiological ligands of the hazel allergen Cor a 1: Complex structures reveal different binding orientation and specificity of mono- and disaccharide derivatives

The global production of hazelnuts is rising, but hazelnut allergies remain common and severe. The PR-10-like allergen Cor a 1, found in hazel pollen and nuts, consists of different isoallergens with over 67 % sequence identity. Cor a 1 binds plant secondary metabolites like the diglycosylated flavo...

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Bibliographic Details
Main Authors: Julian M. Hendrich, Hatice Kara, Kristian Schweimer, Thessa P. Jacob, Maike Schneider, Susanne Baldermann, Birgitta M. Wöhrl
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Food Chemistry: X
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590157525005589
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