Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice»
The paper presents the new version of the clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice » prepared by the Association of Rheumatologists of Russia, the Russian Pain Society, the Russian Gastroenterological Association, the Russian Society of...
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2015-03-01
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Online Access: | https://mrj.ima-press.net/mrj/article/view/590 |
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author | A. E. Karateev E. L. Nasonov N. N. Yakhno V. T. Ivashkin N. V. Chichasova L. I. Alekseeva Yu. A. Karpov M. A. Evseev M. L. Kukushkin A. B. Danilov O. V. Vorobyeva A. V. Amelin D. S. Novikova O. M. Drapkina S. S. Kopenkin G. R. Abuzarova |
author_facet | A. E. Karateev E. L. Nasonov N. N. Yakhno V. T. Ivashkin N. V. Chichasova L. I. Alekseeva Yu. A. Karpov M. A. Evseev M. L. Kukushkin A. B. Danilov O. V. Vorobyeva A. V. Amelin D. S. Novikova O. M. Drapkina S. S. Kopenkin G. R. Abuzarova |
author_sort | A. E. Karateev |
collection | DOAJ |
description | The paper presents the new version of the clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice » prepared by the Association of Rheumatologists of Russia, the Russian Pain Society, the Russian Gastroenterological Association, the Russian Society of Cardiology, the Association of Traumatologists and Orthopedists of Russia, the Association of Interdisciplinary Medicine, and the Russian Association of Palliative Medicine.In our country, NSAIDs are the most important and most popular class of analgesics. Unlike global practice, Russian physicians rather rarely recommend paracetamol as a first-line drug to relieve moderate or severe pain, by giving preference to NSAIDs; the use of opioid analgesics for noncancers is minimized because of tight legal restrictions.NSAIDs are effective and easy-to-use; however, they are far from safe; the administration of these medications may lead to serious gastrointestinal, cardiovascular, renal, and other complications in a number of cases. So the use of NSAIDs should be compulsorily monitored for adverse reactions and the choice of a specific drug for each clinical case should be based on the objective estimation of a ratio of its efficacy to safety.In recent years, there have been fresh data on the use of NSAIDs for different diseases and a few novel representatives of this drug group have appeared on the Russian pharmacological market.This all has necessitated a new version of the guidelines on the rational use of NSAIDs. These are based on the provisions that have high validity and have been confirmed by the results of well-organized clinical and large-scale population-based studies, as well as by their meta-analysis.The guidelines are intended for physicians of all specialties. |
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spelling | doaj-art-b0da17c7ed8a46e18f4f7cf0ff6486e12025-08-04T14:00:33ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2015-03-019142310.14412/1996-7012-2015-1-4-231888Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice»A. E. Karateev0E. L. Nasonov1N. N. Yakhno2V. T. Ivashkin3N. V. Chichasova4L. I. Alekseeva5Yu. A. Karpov6M. A. Evseev7M. L. Kukushkin8A. B. Danilov9O. V. Vorobyeva10A. V. Amelin11D. S. Novikova12O. M. Drapkina13S. S. Kopenkin14G. R. Abuzarova15V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyRussian Cardiology Research-and-Production Complex, Ministry of Health of RussiaCity Clinical Hospital Fifty-Two, Moscow Healthcare DepartmentResearch Institute of General Pathology and PathophysiologyI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaI.P. Pavlov Saint Petersburg State Medical University, Ministry of Health of RussiaV.A. Nasonova Research Institute of RheumatologyI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaN.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaP.A. Herzen Moscow Oncology Research Institute, Branch, Ministry of Health of RussiaThe paper presents the new version of the clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice » prepared by the Association of Rheumatologists of Russia, the Russian Pain Society, the Russian Gastroenterological Association, the Russian Society of Cardiology, the Association of Traumatologists and Orthopedists of Russia, the Association of Interdisciplinary Medicine, and the Russian Association of Palliative Medicine.In our country, NSAIDs are the most important and most popular class of analgesics. Unlike global practice, Russian physicians rather rarely recommend paracetamol as a first-line drug to relieve moderate or severe pain, by giving preference to NSAIDs; the use of opioid analgesics for noncancers is minimized because of tight legal restrictions.NSAIDs are effective and easy-to-use; however, they are far from safe; the administration of these medications may lead to serious gastrointestinal, cardiovascular, renal, and other complications in a number of cases. So the use of NSAIDs should be compulsorily monitored for adverse reactions and the choice of a specific drug for each clinical case should be based on the objective estimation of a ratio of its efficacy to safety.In recent years, there have been fresh data on the use of NSAIDs for different diseases and a few novel representatives of this drug group have appeared on the Russian pharmacological market.This all has necessitated a new version of the guidelines on the rational use of NSAIDs. These are based on the provisions that have high validity and have been confirmed by the results of well-organized clinical and large-scale population-based studies, as well as by their meta-analysis.The guidelines are intended for physicians of all specialties.https://mrj.ima-press.net/mrj/article/view/590clinical guidelinesnonsteroidal anti-inflammatory drugsefficacysafetynsaid gastropathynsaid enteropathycardiovascular eventsnephrotoxicityhepatotoxic reactions |
spellingShingle | A. E. Karateev E. L. Nasonov N. N. Yakhno V. T. Ivashkin N. V. Chichasova L. I. Alekseeva Yu. A. Karpov M. A. Evseev M. L. Kukushkin A. B. Danilov O. V. Vorobyeva A. V. Amelin D. S. Novikova O. M. Drapkina S. S. Kopenkin G. R. Abuzarova Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice» Современная ревматология clinical guidelines nonsteroidal anti-inflammatory drugs efficacy safety nsaid gastropathy nsaid enteropathy cardiovascular events nephrotoxicity hepatotoxic reactions |
title | Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice» |
title_full | Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice» |
title_fullStr | Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice» |
title_full_unstemmed | Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice» |
title_short | Clinical guidelines «Rational use of nonsteroidal anti-inflammatory drugs (NSAIDs) in clinical practice» |
title_sort | clinical guidelines rational use of nonsteroidal anti inflammatory drugs nsaids in clinical practice |
topic | clinical guidelines nonsteroidal anti-inflammatory drugs efficacy safety nsaid gastropathy nsaid enteropathy cardiovascular events nephrotoxicity hepatotoxic reactions |
url | https://mrj.ima-press.net/mrj/article/view/590 |
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