Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study

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Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study

Metabolic reprogramming within the tumor microenvironment significantly affects cancer progression by shifting toward aerobic glycolysis and lactate production, while also supporting mitochondrial oxidative phosphorylation. The glyoxalase system, comprising GLO-1 and GLO-2, maintains metabolic homeo...

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Bibliographic Details
Main Authors:	Ali M. Alaseem, Jehad A. Aldali, Glowi Alasiri, Muhanad Alhujaily, Khalid I. AlHussaini, Osama A. AlKhamees
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Series:	Frontiers in Oncology
Subjects:	tumor microenvironment metabolic reprogramming glyoxalase system GLO-1 expression cancer progression
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1610886/full
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