The study of cross-reactivity of therapeutic drugs based on monoclonal antibodies on human tissues: basic approaches and methodological techniques
Tissue cross-reactivity (TCR) studies are screening immunohistochemical (IHC) assays, usually conducted on frozen human and animal tissues. This study is obligatory for getting the permission for clinical trials in Russia for all innovative therapeutic products based on monoclonal antibodies or anti...
Saved in:
Main Authors: | T. Y. Ostroukhova, V. A. Ivanov, E. L. Morozova, R. A. Ivanov |
---|---|
Format: | Article |
Language: | Russian |
Published: |
Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
2018-02-01
|
Series: | Биопрепараты: Профилактика, диагностика, лечение |
Subjects: | |
Online Access: | https://www.biopreparations.ru/jour/article/view/70 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Development and validation of a method for determination of Eculizumab concentration in human plasma by biolayer interferometry
by: V. M. Simonov, et al.
Published: (2018-02-01) -
Temporal TCR dynamics and epitope diversity mark recovery in severe COVID-19 patients
by: Kriti Khare, et al.
Published: (2025-07-01) -
dandelionR: Single-cell immune repertoire trajectory analysis in R
by: Jiawei Yu, et al.
Published: (2025-01-01) -
DNA-demethylation by DAC induces MAGE expression and MAGE-specific T cell reactivity against tumors but also healthy cell subsets
by: Marije A.J. de Rooij, et al.
Published: (2025-09-01) -
Development of iPSC-derived T cells targeting EGFR neoantigens in non-small cell lung cancer
by: Kouta Niizuma, et al.
Published: (2025-09-01)