A dual fluorescence-based reporter assay for real-time determination of siRNA- and antisense oligonucleotide-mediated knockdown
In recent years, many tools have been developed for targeted treatments of cancer or rare diseases including nucleic acid (NA)-based therapeutics. One of the developmental caveats is the assessment of their functionality in vivo. We therefore developed a sensitive dual fluorescence-based FluoroDetec...
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Main Authors: | Felix Heß, Margarete Odenthal, Elena Wasserburger-Zichel, Christina Grimm, Michal R. Schweiger |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-09-01
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Series: | Molecular Therapy: Nucleic Acids |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2162253125001854 |
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