A dual fluorescence-based reporter assay for real-time determination of siRNA- and antisense oligonucleotide-mediated knockdown

In recent years, many tools have been developed for targeted treatments of cancer or rare diseases including nucleic acid (NA)-based therapeutics. One of the developmental caveats is the assessment of their functionality in vivo. We therefore developed a sensitive dual fluorescence-based FluoroDetec...

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Auteurs principaux: Felix Heß, Margarete Odenthal, Elena Wasserburger-Zichel, Christina Grimm, Michal R. Schweiger
Format: Article
Langue:anglais
Publié: Elsevier 2025-09-01
Collection:Molecular Therapy: Nucleic Acids
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2162253125001854
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