Separated or joint models of repeated multivariate data to estimate individuals' disease trajectories with application to scleroderma.

Estimating a patient's disease trajectory as defined by clinical measures is an essential task in medicine. Given multiple biomarkers, there is a practical choice of whether to estimate the joint distribution of all biomarkers in a single model or to model the univariate marginal distribution o...

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Bibliographic Details
Main Authors: Ji Soo Kim, Ami A Shah, Laura K Hummers, Scott L Zeger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320414
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