Characterization of holins, the membrane proteins of coliphage ASEC2201: a genomewide in silico approach

Characterization of holins, the membrane proteins of coliphage ASEC2201: a genomewide in silico approach

Drug-resistant Escherichia coli poses a significant healthcare burden, driving the search for novel antimicrobials. We have previously done the isolation and whole-genome sequencing of ASEC2201, a novel coliphage derived from multidrug-resistant clinical E. coli strains. Here, we report the identifi...

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Bibliographic Details
Main Authors: Humaira Saeed, Sudhaker Padmesh, Aditi Singh, Sujeet Pratap Singh, Mohammed Haris Siddiqui, Manodeep Sen, Imran Hussain, Mirza Masroor Ali Beg
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
transmembrane domain
phage-mediated lysis
ASEC2201
protein 3D structure
functional annotation
holins
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1550594/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1550594/full

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