Rapid cochlear gene therapy in adult deaf mice: Vglut3 rescue via AAV8 achieves day-1 hearing restoration
Genetic hearing loss, caused by mutations in critical auditory genes, has seen promising advances through gene therapy, yet the temporal dynamics of early-stage auditory functional recovery and therapeutic transgene expression patterns following intervention remain uncharacterized in preclinical dea...
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Main Authors: | Ting Zhang, Rongqun Zhai, Mengli Liu, Hongen Xu, Liang Wang, Wenxue Tang, Bei Chen, Xingle Zhao |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-09-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050125001342 |
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