Therapeutic Potential of Proanthocyanidins in Dentistry: A Focus on Periodontal Disease and on Dental Implants in Osteoporotic Patients

QR Code

Therapeutic Potential of Proanthocyanidins in Dentistry: A Focus on Periodontal Disease and on Dental Implants in Osteoporotic Patients

Proanthocyanidins (PACs), also called condensed tannins, are oligomers or polymers composed of flavan-3-ols. This review aimed to explore the potential role of PACs in ameliorating oral health problems, with a particular focus on their effects within the intestine—especially the colon, where most or...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yoshimi Niwano, Shunichi Shishido, Midori Shirato, Hidetsugu Kohzaki, Keisuke Nakamura
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Antioxidants
Subjects:	proanthocyanidins oral health problems osteoporosis gut barrier function Nrf2 signaling pathway
Online Access:	https://www.mdpi.com/2076-3921/14/7/850
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Effects of Proanthocyanidins on Growth Performance, Intestinal Inflammation and Barrier Function, and Bile Acid Metabolism-Related Genes in Weaned Piglets Challenged with Lipopolysaccharide
by: Aiying Yu, et al.
Published: (2025-06-01)

Review on the biosynthesis of anthocyanidins and proanthocyanidins in rice and their impact on rice quality
by: ZHOU Yufeng, et al.
Published: (2024-06-01)

Comparative analysis of the effectiveness of antibiotic therapy and combined administration of antibiotics, lactobacilli, and proanthocyanidins for asymptomatic bacteriuria in young pregnant women: A randomized prospective study
by: I. V. Sakhautdinova, et al.
Published: (2024-08-01)

Cross-linked nanoparticles of silk fibroin with proanthocyanidins as a promising vehicle of indocyanine green for photo-thermal therapy of glioma
by: De-Li ZhuGe, et al.
Published: (2019-12-01)

Revealing the multi-target destruction induced by proanthocyanidins against Acetobacter sp. at the molecular level
by: Er-Fang Ren, et al.
Published: (2025-07-01)

Effect of grape seed proanthocyanidin extract on intestine, slaughter performance, lipid metabolism and meat quality of broilers
by: HOU Fuyin, et al.
Published: (2019-02-01)

Prebiotic-like Effects of Proanthocyanidin-Rich Aronia Extract Supplementation on Gut Microbiota Composition and Function in the Twin-M-SHIME<sup>®</sup> Model
by: Blanca Elizabeth Ruiz-Álvarez, et al.
Published: (2025-05-01)

Isolation and Structure Elucidation of Three Dimeric A-type Proanthocyanidins from <i>Empetrum Nigrum</i> L.
by: A. O. Ponkratova, et al.
Published: (2021-05-01)

Hylotelephium mingjinianum Extract Attenuates Oxidative Stress and Inflammation in Experimental Periodontitis
by: Yuan L, et al.
Published: (2025-06-01)

THE COMPARISON OF PLASMA MALONDIALDEHYDE LEVELS AMONG OSTEOPOROTIC AND NON-OSTEOPOROTIC POSTMENOPAUSAL WOMEN
by: Innawati Jusup, et al.
Published: (2020-11-01)

Iridoids derived from Valeriana jatamansi Jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathway
by: Yongzhi He, et al.
Published: (2025-07-01)

EPIDEMIOLOGY OF OSTEOPOROTIC FRACTURES OF VERTEBRAS IN ELDERLY AND SENILE PERSONS
by: V. G. Pustozerov, et al.
Published: (2012-09-01)

Modulation of the KEAP1-NRF2 pathway by Erianin: A novel approach to reduce psoriasiform inflammation and inflammatory signaling
by: Yan Hongmei, et al.
Published: (2025-07-01)

EFFICACY OF PHYSICAL EXERCISES IN PATIENTS WITH OSTEOPOROTIC VERTEBRAL FRACTURES
by: Lyudmila P Evstigneeva, et al.
Published: (2014-03-01)

Insights into the role of Nrf2 in vitiligo pathogenesis: a target for herbal medicine
by: Abdel Qawasmeh, et al.
Published: (2025-07-01)

Osteoporotic vertebral fractures: an update
by: Daskalakis Ioannis I., et al.
Published: (2025-01-01)

Activation of the Nrf2 Signaling Pathway as a Therapeutic Strategy Against Periodontal Disease: A Narrative Review
by: Sarmistha Saha, et al.
Published: (2025-07-01)

A study of a complex of bioactive compounds in the fruits of promising blue honeysuckle (<i>Lonicera caerulea</i> L.) cultivars
by: I. B. Perova, et al.
Published: (2023-04-01)

Incidence of osteoporotic femur fractures in old people living in Kemerovo
by: T A Raskina, et al.
Published: (2013-03-01)

glucocorticoid osteoporosis; osteoporotic fracture; bisphosphonates; FRAX algorithm
by: Natalia Vladimirovna Toroptsova, et al.
Published: (2013-12-01)

Ertugliflozin, a SGLT-2 Inhibitor, Guards Against Thioacetamide-induced Liver Fibrosis: The Nrf2/HO-1 and TLR4/ TGF-β1 Pathways
by: Nourhan Hassan, et al.
Published: (2025-07-01)

Design, Synthesis, and Evaluation of Nitroxide Radical Derivatives Based on Rhein as Potential Anti-Aging Agents Targeting the Keap1-Nrf2 Pathway
by: Wang J, et al.
Published: (2025-06-01)

Effective-Component Compatibility of Bufei Yishen Formula III Protects Lung Air-Blood Barrier by Regulating the Oxidative Stress: via the Nuclear Factor-E2-Related Factor 2 Pathway
by: Xu K, et al.
Published: (2025-07-01)

Percutaneous Cementing Procedures in Osteoporotic Vertebral Compression Fractures: A Narrative Review
by: Karthik Kailash, et al.
Published: (2025-05-01)

Advancement in Fixation Techniques for Osteoporotic Bone: A Narrative Review
by: Abhinandan Reddy Mallepally, et al.
Published: (2025-05-01)

Pain Localization Shift During the Convalescence Period of Osteoporotic Vertebral Compression Fracture
by: Oded Hershkovich, et al.
Published: (2025-05-01)

GENES DETERMINING THE SYNTHESIS OF LAVONOID AND MELANIN PIGMENTS IN BARLEY
by: O. Yu. Shoeva, et al.
Published: (2018-05-01)

Effect of whole-plant mulberry supplementation on testis development and antioxidant capacity in Hu rams
by: Jiamei Liu, et al.
Published: (2025-07-01)

Effect of Postharvest Ripening on the Phytochemical Composition and Antioxidant Properties of Fruits from Ten Plum (<i>Prunus domestica</i> L.) Cultivars
by: Monika Mieszczakowska-Frąc, et al.
Published: (2025-05-01)

Estimation of Serum Osteocalcin Levels in Osteoporotic Postmenopausal Iraqi Women with Type 2 Diabetes Mellitus
by: Baghdad Science Journal
Published: (2014-12-01)

Fucoxanthin mitigates aflatoxin B1-triggered hepatotoxicity in HepG2 cells via modulation of oxidative stress, inflammatory cytokines, and caspases cascade
by: Ekramy M. Elmorsy, et al.
Published: (2025-09-01)

The role of Nrf2 signaling pathway in diabetic cardiomyopathy: from pathogenesis to traditional Chinese medicine interventions
by: Huixian Gu, et al.
Published: (2025-07-01)

Oxidative stress responses in Ehrlichia-induced sepsis: mechanisms and implications in pathogenesis
by: Aditya Kumar Sharma, et al.
Published: (2025-07-01)

Protective Effects of Fish Oil Against Brain Impairment in Rats with Chronic Ethanol-Induced Liver Damage Involving the NRF2 Pathway and Oxidative Stress
by: Qian Xiao, et al.
Published: (2025-06-01)

Secondary prevention of osteoporosis and osteoporotic fractures in real clinical practice and possibilities of its improvement with strontium ranelate
by: Nataliya Vladimirovna Toroptsova
Published: (2012-03-01)

The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis
by: A. О. Efremova, et al.
Published: (2021-02-01)

Structural characterization and alleviation on osteoporotic of polysaccharide purified from Psidium guajava L. leaves
by: Meng Meng, et al.
Published: (2025-08-01)

HNRNPC stabilizes m6A-modified AC145207.5 to accelerate tumorigenesis in colorectal cancer by impeding the Nrf2/GPX4 axis-mediated ferroptosis
by: Dan Liu, et al.
Published: (2025-08-01)

DMF, an activator of Nrf2, could mitigate cholic-acid-induced liver damage in high-fat diet
by: Diana Abu-Halaka, et al.
Published: (2025-07-01)

Unveiling the sweet culprit: Excessive fructose intake leading to kidney injury through hypoxanthine accumulation
by: Gaoxiang Ai, et al.
Published: (2025-08-01)