MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES
Close clinical and phylogenetic relationship of skin conditions, mental health and disorders of the hepatobiliary system was established. The aim of the study was to evaluate the efficacy of systemic antifungal monotherapy (terbinafine) plus S-adenosylmethionine (AdoMet, SAMe), as compared to terbin...
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| Format: | Article |
| Language: | Russian |
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SINAPS LLC
2016-12-01
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| Series: | Архивъ внутренней медицины |
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| Online Access: | https://www.medarhive.ru/jour/article/view/603 |
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| author | E. V. Gerasimchuk V. V. Gladko M. Y. Gerasimchuk |
| author_facet | E. V. Gerasimchuk V. V. Gladko M. Y. Gerasimchuk |
| author_sort | E. V. Gerasimchuk |
| collection | DOAJ |
| description | Close clinical and phylogenetic relationship of skin conditions, mental health and disorders of the hepatobiliary system was established. The aim of the study was to evaluate the efficacy of systemic antifungal monotherapy (terbinafine) plus S-adenosylmethionine (AdoMet, SAMe), as compared to terbinafine alone, in patients (n=108) with onychomycosis and different chronic itching dermatoses. Management with terbinafine plus hepatoprotective agent was associated with better therapy response, SAMe supplementation seem to be effective in the prevention of liver injury, normalization of biochemical parameters and neuropsychological evaluation of patients. |
| format | Article |
| id | doaj-art-ad28d29d3c7f491880ca36467dba8b97 |
| institution | Matheson Library |
| issn | 2226-6704 2411-6564 |
| language | Russian |
| publishDate | 2016-12-01 |
| publisher | SINAPS LLC |
| record_format | Article |
| series | Архивъ внутренней медицины |
| spelling | doaj-art-ad28d29d3c7f491880ca36467dba8b972025-08-04T14:09:45ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642016-12-0166687110.20514/2226-6704-2016-6-6-68-71567MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIESE. V. Gerasimchuk0V. V. Gladko1M. Y. Gerasimchuk2Head of the department of dermatology, Branch 6, A.Vishnevsky 3 Central Military Hospital of Russian Ministry of defense, Moscow, RussiaFGBOU VPO “MGUPP’s” IMSTDepartment of psychiatry and narcology, I. M. Sechenov Moscow state medical University, Moscow, RussiaClose clinical and phylogenetic relationship of skin conditions, mental health and disorders of the hepatobiliary system was established. The aim of the study was to evaluate the efficacy of systemic antifungal monotherapy (terbinafine) plus S-adenosylmethionine (AdoMet, SAMe), as compared to terbinafine alone, in patients (n=108) with onychomycosis and different chronic itching dermatoses. Management with terbinafine plus hepatoprotective agent was associated with better therapy response, SAMe supplementation seem to be effective in the prevention of liver injury, normalization of biochemical parameters and neuropsychological evaluation of patients.https://www.medarhive.ru/jour/article/view/603onychomycosisdepressionademetionine (s-adenosylmethionine, adomet, same)hepatoprotectorterbinafine |
| spellingShingle | E. V. Gerasimchuk V. V. Gladko M. Y. Gerasimchuk MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES Архивъ внутренней медицины onychomycosis depression ademetionine (s-adenosylmethionine, adomet, same) hepatoprotector terbinafine |
| title | MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES |
| title_full | MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES |
| title_fullStr | MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES |
| title_full_unstemmed | MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES |
| title_short | MEDICAL MYCOLOGY, PSYCHIATRY, HEPATOLOGY — ACTUAL INTERDISCIPLINARY CLINICAL PROBLEM, SOLUTION DEVELOPMENT, TREATMENT PECULIARITIES |
| title_sort | medical mycology psychiatry hepatology actual interdisciplinary clinical problem solution development treatment peculiarities |
| topic | onychomycosis depression ademetionine (s-adenosylmethionine, adomet, same) hepatoprotector terbinafine |
| url | https://www.medarhive.ru/jour/article/view/603 |
| work_keys_str_mv | AT evgerasimchuk medicalmycologypsychiatryhepatologyactualinterdisciplinaryclinicalproblemsolutiondevelopmenttreatmentpeculiarities AT vvgladko medicalmycologypsychiatryhepatologyactualinterdisciplinaryclinicalproblemsolutiondevelopmenttreatmentpeculiarities AT mygerasimchuk medicalmycologypsychiatryhepatologyactualinterdisciplinaryclinicalproblemsolutiondevelopmenttreatmentpeculiarities |