Ectopic ULBP2 Is Associated with Decreased NKG2D Expression in CD8<sup>+</sup> T Cells Under T Cell-Modulatory Conditions in a Murine Tumor Model
UL16-binding protein 2 (ULBP2), a ligand for the activating receptor NKG2D, plays a dual role in tumor immunity, promoting immune activation or suppression, depending on the context. To investigate its impact on CD4<sup>+</sup>CD25<sup>+</sup> T cell-targeted immunotherapies,...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-06-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/14/12/893 |
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