Quantification and Validation of a HPLC-UV Method for Simultaneous Analysis of Nitrosoamine Impurities (NDMA, NDEA and NDIPA) in Losartan
Impurity profiling is an important aspect in drug therapy for its safety and efficacy. The study of impurities of sartans, the first line antihypertensive drugs, has become critical due to presence of cancer causing N-nitrosodimethylamine (NDMA), N-nitrosodiethylamine (NDEA) and N-nitrosodi...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Krupanidhi College of Pharmacy
2021-12-01
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| Series: | Journal of Pharmaceutical Research |
| Online Access: | https://jopcr.com/articles/quantification-and-validation-of-a-hplc-uv-method-for-simultaneous-analysis-of-nitrosoamine-impurities-ndma-ndea-and-ndipa-in-losartan |
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