Association of RDoC dimensions with post mortem brain transcriptional profiles in Alzheimer's disease

Abstract INTRODUCTION Neuropsychiatric symptoms are common in people with Alzheimer's disease (AD) across all severity stages. Their heterogeneous presentation and variable temporal association with cognitive decline suggest shared and distinct biological mechanisms. We hypothesized that specif...

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Bibliographic Details
Main Authors: Weiqian Jiang, Jonathan Vogelgsang, Shu Dan, Peter Durning, Thomas H. McCoy, Sabina Berretta, Torsten Klengel
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
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Online Access:https://doi.org/10.1002/dad2.70103
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