A Rare Case of Pulmonary Leiomyosarcoma
Leiomyosarcoma commonly occurs in the abdomen, retroperitoneum, large blood vessels, and uterus[1]. Cardiac leiomyosarcoma is a rare and highly aggressive sarcoma. We reported a case of a 63-year-old male with pulmonary artery leiomyosarcoma. Transthoracic echocardiography showed a large 4.4×2.3 cm...
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| Language: | English |
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Interna Publishing
2023-03-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/1898 |
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| author | Jialin He Yun Tang Fei Zhao Bo Zheng Shihai Tang Juan Gong Li Wang Yang Zhou |
| author_facet | Jialin He Yun Tang Fei Zhao Bo Zheng Shihai Tang Juan Gong Li Wang Yang Zhou |
| author_sort | Jialin He |
| collection | DOAJ |
| description | Leiomyosarcoma commonly occurs in the abdomen, retroperitoneum, large blood vessels, and uterus[1]. Cardiac leiomyosarcoma is a rare and highly aggressive sarcoma. We reported a case of a 63-year-old male with pulmonary artery leiomyosarcoma. Transthoracic echocardiography showed a large 4.4×2.3 cm hypoechoic mass in the right ventricular outflow tract and pulmonary artery. Computed tomography pulmonary angiography showed a filling defect in a similar location. The initial impression was PE, but a tumor was not ruled out. An emergency surgery was performed due to progressively worse chest distress and dyspnea. A yellow mass that had adhered to the ventricular septum and pulmonary artery wall was detected to be compressing the pulmonary valve. Immunohistochemistry confirmed tumor cells positive staining for Desmin and smooth muscle actin and negative staining for S-100, CD34, myogenin, or myoglobin, and KI67(+)80%, indicating leiomyosarcoma. Pulmonary leiomyosarcoma showed a side-inserted heart chamber filling defect in CTA and should be excised when the patient suddenly deteriorated.
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| format | Article |
| id | doaj-art-ab761f8aa1d84331aead5f68a7e74e7f |
| institution | Matheson Library |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-ab761f8aa1d84331aead5f68a7e74e7f2025-07-14T07:00:53ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322023-03-01551A Rare Case of Pulmonary LeiomyosarcomaJialin He0Yun Tang1Fei Zhao2Bo Zheng3Shihai Tang4Juan Gong5Li Wang6Yang Zhou7Department of Cardiothoracic Surgery, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaDepartment of Geriatric, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaDepartment of Cardiothoracic Surgery, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaDepartment of Cardiothoracic Surgery, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaDepartment of Cardiothoracic Surgery, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaDepartment of Cardiothoracic Surgery, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaDepartment of Geriatric, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaDepartment of Cardiothoracic Surgery, People’s Hospital of Leshan, Leshan, Sichuan Province, ChinaLeiomyosarcoma commonly occurs in the abdomen, retroperitoneum, large blood vessels, and uterus[1]. Cardiac leiomyosarcoma is a rare and highly aggressive sarcoma. We reported a case of a 63-year-old male with pulmonary artery leiomyosarcoma. Transthoracic echocardiography showed a large 4.4×2.3 cm hypoechoic mass in the right ventricular outflow tract and pulmonary artery. Computed tomography pulmonary angiography showed a filling defect in a similar location. The initial impression was PE, but a tumor was not ruled out. An emergency surgery was performed due to progressively worse chest distress and dyspnea. A yellow mass that had adhered to the ventricular septum and pulmonary artery wall was detected to be compressing the pulmonary valve. Immunohistochemistry confirmed tumor cells positive staining for Desmin and smooth muscle actin and negative staining for S-100, CD34, myogenin, or myoglobin, and KI67(+)80%, indicating leiomyosarcoma. Pulmonary leiomyosarcoma showed a side-inserted heart chamber filling defect in CTA and should be excised when the patient suddenly deteriorated. http://www.actamedindones.org/index.php/ijim/article/view/1898Pulmonary leiomyosarcomaPulmonary embolismDiagnosis |
| spellingShingle | Jialin He Yun Tang Fei Zhao Bo Zheng Shihai Tang Juan Gong Li Wang Yang Zhou A Rare Case of Pulmonary Leiomyosarcoma Acta Medica Indonesiana Pulmonary leiomyosarcoma Pulmonary embolism Diagnosis |
| title | A Rare Case of Pulmonary Leiomyosarcoma |
| title_full | A Rare Case of Pulmonary Leiomyosarcoma |
| title_fullStr | A Rare Case of Pulmonary Leiomyosarcoma |
| title_full_unstemmed | A Rare Case of Pulmonary Leiomyosarcoma |
| title_short | A Rare Case of Pulmonary Leiomyosarcoma |
| title_sort | rare case of pulmonary leiomyosarcoma |
| topic | Pulmonary leiomyosarcoma Pulmonary embolism Diagnosis |
| url | http://www.actamedindones.org/index.php/ijim/article/view/1898 |
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