A Clinical Study of the Safety and Tolerability of Live Nasal Vaccines for the Prevention of Pertussis

QR Code

A Clinical Study of the Safety and Tolerability of Live Nasal Vaccines for the Prevention of Pertussis

Introduction. Due to the growth of laboratory-confirmed cases of pertussis among adolescents and adults, the spread of latent form of disease and the identification of asymptomatic carriage of the pathogen, the need arose to create a new vaccine against B. pertussis. On the basis of N. F. Gamaleya F...

Full description

Saved in:

Bibliographic Details
Main Authors:	A. Yu. Medkova, A. A. Lidzhieva, E. G. Semin, L. N. Sinyashina, R. A. Sioundioukova, I. N. Dyakov, L. V. Kolobukhina, I. S. Kruzhkova, L N. Merkulova, M. G. Rusanova, N. A. Antipyat, S. V. Smetanina, G. I. Karataev
Format:	Article
Language:	Russian
Published:	LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2021-02-01
Series:	Разработка и регистрация лекарственных средств
Subjects:	pertussis live vaccine anti-pertussis vaccine
Online Access:	https://www.pharmjournal.ru/jour/article/view/754
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Development of a Method and a Scheme for the Use of a Live Recombinant Vaccine "GamLPV". Safety and Tolerability of Double Intranasal Vaccination of Healthy Adult Volunteers
by: G. I. Karataev, et al.
Published: (2022-09-01)

Immunogenicity of GamLPV, an intranasal live vaccine for pertussis prevention, in adult volunteers: a blind, randomised, placebo-controlled trial to optimise the method and schedule of administration
by: A. A. Lidzhieva, et al.
Published: (2025-04-01)

Pertussis vaccines and the role of <I>Bordetella pertussis</I> lipooligosaccharide in the immune response to pertussis infection and vaccination
by: I. A. Alekseeva, et al.
Published: (2021-03-01)

Pre-Clinical Toxicity Study and Safety Assessment of Candidate Live Pertussis Vaccine for Intranasal Administration
by: L. N. Sinyashina, et al.
Published: (2019-01-01)

Evaluation of Immunobiological Properties of Bordetella pertussis Vaccine Strains
by: I. A. Alekseeva, et al.
Published: (2018-03-01)

Effects of pertussis toxin and <i>Bordetella pertussis</i> lipo-oligosaccharide on the specific toxicity and potency of whole-cell pertussis vaccines
by: I. A. Alekseeva, et al.
Published: (2023-10-01)

PERTUSSIS IS COMING BACK? IMPROVEMENT OF FORGOTTEN CHILDHOOD INFECTION CONTROL
by: M. V. Fedoseenko, et al.
Published: (2012-04-01)

Epizootic pertussis focus of hamadryad baboons
by: A. Yu. Medkova, et al.
Published: (2015-11-01)

The interdisciplinary Meeting of Experts’s Resolution «Unresolved Questions of Pertussis Epidemiology in the Russian Federation and the New Possibilities for Vaccination»
by: Article Editorial
Published: (2018-09-01)

Safety of Combination Vaccines with Whole Cell Pertussis Component
by: O. V. Perelygina, et al.
Published: (2016-12-01)

Pertussis in the Voronezh Region: Epidemiology and Vaccination
by: N. P. Mamchik, et al.
Published: (2020-05-01)

Assessment of the timeliness of vaccination against pertussis in children of the first year of life and the reasons for the violation of the vaccination schedule
by: T. M. Chernova, et al.
Published: (2021-07-01)

Comparative analysis of whole-cell and acellular pertussis vaccines efficacy in preventing pertussis
by: I. A. Alekseeva, et al.
Published: (2018-02-01)

Influence of storage conditions on the toxicity of whole-cell pertussis vaccine in outbred mice
by: I. A. Alekseeva, et al.
Published: (2025-04-01)

Estimation of Consistency of Production of the Pertussis Component of DTP Vaccine in Terms of Immunogenic Activity and Specific Safety Using Shewhart Charts
by: I. A. Alekseeva, et al.
Published: (2018-12-01)

Safety, immunogenicity, and protective efficacy of the intranasal live pertussis vaccine GamLPV in an infant monkey model (<i>Papio hamadryas</i>)
by: D. T. Kubrava, et al.
Published: (2024-12-01)

The economic evaluation of a vaccination against pertussis infection in children in Moscow
by: S. V. Svetlichnaya, et al.
Published: (2023-10-01)

Transmission Dynamics and Parameters for Pertussis during School-Based Outbreak, South Korea, 2024
by: U. Jin Cho, et al.
Published: (2025-07-01)

Acellular Pertussis Vaccine from Antigens of Freshly Isolated and Vaccine Strains of Bordetella pertussis with Different Genotypic Characteristics
by: E. M. Zaitsev, et al.
Published: (2021-09-01)

Pertussis resurgence: epidemiological trends, pathogenic mechanisms, and preventive strategies
by: Yaping Sheng, et al.
Published: (2025-07-01)

Pertussis vaccination: problems, possible solutions
by: S. M. Kharit, et al.
Published: (2020-06-01)

Current epidemiological characteristics of pertussis in the Russian Federation
by: A. V. Stepenko, et al.
Published: (2020-06-01)

Protective Activity and Safety of Acellular Pertussis Vaccine from Vaccine and Freshly Isolated Strain Bordetella pertussis
by: E. M. Zaitsev, et al.
Published: (2017-04-01)

Post-Vaccination Immunity to Pertussis in Children of Lipetsk, New Management Capabilitiesto Infection
by: T. V. Timofeeva, et al.
Published: (2019-06-01)

DPT vaccine evolution: Formulation differences, standardisation issues, and development prospects
by: E. I. Komarovskaya, et al.
Published: (2025-04-01)

Urgent issues of epidemiology, clinical picture, diagnostics and prevention of pertussis at the present stage
by: A. V. Vasyunin, et al.
Published: (2021-06-01)

Criteria for Assessing the Epidemiological Situation of Pertussis in Russian Federation
by: A. A. Basov, et al.
Published: (2024-03-01)

Pertussis in a child of the first month of life from family contact
by: O. V. Iozefovich, et al.
Published: (2021-07-01)

Expression of adhesins by some “Bordetella pertussis” strains isolated in Romania in different time periods
by: Georgeta Cristina OPREA, et al.
Published: (2018-12-01)

The Epidemiological Situation with Pertussis in the Yaroslavl Region and its Development Trends
by: T. A. Druzhinina, et al.
Published: (2025-07-01)

PERTUSSIS — INFECTION NOT UNDER COMPLETE CONTROL
by: V. K. Tatochenko
Published: (2014-03-01)

Evaluation of the economic efficacy of vaccination against pertussis based on real-world data
by: S. V. Svetlichnaya, et al.
Published: (2023-03-01)

The timely vaccination rate of pertussis-containing vaccines among children born in Henan province from 2012 to 2021: a surveillance data analysis
by: Changshuang WANG, et al.
Published: (2025-06-01)

Risk factors of complicated course of pertussis infection and methods of their correction at the ambulatory stage according to modern trends of specific immunization
by: E. I. Krasnova, et al.
Published: (2021-06-01)

TOLERANCE OF CHILDREN OLDER THAN 4 YEARS TO ACELLULAR DPT-VACCINES: RESULTS OF A RETROSPECTIVE STUDY
by: A. G. Gaivoronskaya, et al.
Published: (2017-02-01)

Pertussis hospitalizations in France (2008–2020): A real-world retrospective analysis of incidence and costs based on the French National Health Data System
by: Juan C. Vargas-Zambrano, et al.
Published: (2025-08-01)

Analysis of a Serological Study of Pertussis among Children and Adolescents in the Republic of Kazakhstan
by: M. A. Smagul, et al.
Published: (2023-03-01)

Clinico-Epidemiological And Microbiological Evolution Of Pertussis
by: I. V. Babachenko
Published: (2014-09-01)

Incidence of vaccine preventable diseases in pediatric population of Latvia
by: Renāta Klagiša, et al.
Published: (2016-06-01)

FEATURES OF GENOTYPiNG VARIABILITY OF STRAINS OF BORDETELLA PERTUSSIS ALLOCATED FROM PATIENTS WITH WHOOPING COUGH IN RUSSIA
by: V. A. Aleshkin, et al.
Published: (2012-09-01)