Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy
Objective of our work was to evaluate MEPs characteristics in children with acute inflammatory demyelinating polyneuropathy and evaluate usefulness of TMS as an additional diagnostic method in this disorder.Methods. 20 healthy children (7–14 years old, average 12 years, 7 females, 13 males) without...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Journal Infectology
2016-07-01
|
| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/481 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839572079121268736 |
|---|---|
| author | V. B. Voitenkov J. Málly N. V. Skripchenko A. V. Klimkin |
| author_facet | V. B. Voitenkov J. Málly N. V. Skripchenko A. V. Klimkin |
| author_sort | V. B. Voitenkov |
| collection | DOAJ |
| description | Objective of our work was to evaluate MEPs characteristics in children with acute inflammatory demyelinating polyneuropathy and evaluate usefulness of TMS as an additional diagnostic method in this disorder.Methods. 20 healthy children (7–14 years old, average 12 years, 7 females, 13 males) without any signs of neurological disorders were enrolled as controls and 37 patients (8–13 years old, average 11 years, 19 females, 18 males) with AIDP were enrolled as the main group. EMG and TMS were performed on 3–7 day from the onset of the first symptoms. Cortical and lumbar MEP`s latencies, shapes and amplitudes and CMCT were averaged and analyzed.Results. Significant differences between children with AIDP and controls on latencies of both cortical and lumbar MEPs were registered. Cortical MEPs shapes were disperse in 100% of the cases, and lumbar MEPs were disperse in 57% of the cases. Amplitudes changes for both lumbar and cortical MEPs were not significant.Conclusions. Diagnostic transcranial magnetic stimulation on the early stage of the acute demyelinating polyneuropathy in children may be implemented as the additional tool. Main finding in this population is lengthening of the latency of cortical and lumbar motor evoked potentials. Disperse shape of the lumbar MEPs may also be used as the early sign of the acute demyelization of the peripheral nerves. |
| format | Article |
| id | doaj-art-a94c1643145b46f99dee6ea25e14f69d |
| institution | Matheson Library |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2016-07-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-a94c1643145b46f99dee6ea25e14f69d2025-08-04T14:25:43ZrusJournal InfectologyЖурнал инфектологии2072-67322016-07-01827277478Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathyV. B. Voitenkov0J. Málly1N. V. Skripchenko2A. V. Klimkin3Scienсе Research Institute of Children’s InfectionsInstitute of NeurorehabilitationScienсе Research Institute of Children’s InfectionsScienсе Research Institute of Children’s InfectionsObjective of our work was to evaluate MEPs characteristics in children with acute inflammatory demyelinating polyneuropathy and evaluate usefulness of TMS as an additional diagnostic method in this disorder.Methods. 20 healthy children (7–14 years old, average 12 years, 7 females, 13 males) without any signs of neurological disorders were enrolled as controls and 37 patients (8–13 years old, average 11 years, 19 females, 18 males) with AIDP were enrolled as the main group. EMG and TMS were performed on 3–7 day from the onset of the first symptoms. Cortical and lumbar MEP`s latencies, shapes and amplitudes and CMCT were averaged and analyzed.Results. Significant differences between children with AIDP and controls on latencies of both cortical and lumbar MEPs were registered. Cortical MEPs shapes were disperse in 100% of the cases, and lumbar MEPs were disperse in 57% of the cases. Amplitudes changes for both lumbar and cortical MEPs were not significant.Conclusions. Diagnostic transcranial magnetic stimulation on the early stage of the acute demyelinating polyneuropathy in children may be implemented as the additional tool. Main finding in this population is lengthening of the latency of cortical and lumbar motor evoked potentials. Disperse shape of the lumbar MEPs may also be used as the early sign of the acute demyelization of the peripheral nerves.https://journal.niidi.ru/jofin/article/view/481acute inflammatory demyelinating polyneuropathyemgtmsmep |
| spellingShingle | V. B. Voitenkov J. Málly N. V. Skripchenko A. V. Klimkin Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy Журнал инфектологии acute inflammatory demyelinating polyneuropathy emg tms mep |
| title | Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy |
| title_full | Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy |
| title_fullStr | Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy |
| title_full_unstemmed | Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy |
| title_short | Diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy |
| title_sort | diagnostic transcranial magnetic stimulation in children with acute inflammatory demyelinating polyneuropathy |
| topic | acute inflammatory demyelinating polyneuropathy emg tms mep |
| url | https://journal.niidi.ru/jofin/article/view/481 |
| work_keys_str_mv | AT vbvoitenkov diagnostictranscranialmagneticstimulationinchildrenwithacuteinflammatorydemyelinatingpolyneuropathy AT jmally diagnostictranscranialmagneticstimulationinchildrenwithacuteinflammatorydemyelinatingpolyneuropathy AT nvskripchenko diagnostictranscranialmagneticstimulationinchildrenwithacuteinflammatorydemyelinatingpolyneuropathy AT avklimkin diagnostictranscranialmagneticstimulationinchildrenwithacuteinflammatorydemyelinatingpolyneuropathy |