Early to Late VSV-G Expression in AcMNPV BV Enhances Transduction in Mammalian Cells but Does Not Affect Virion Yield in Insect Cells

Early to Late VSV-G Expression in AcMNPV BV Enhances Transduction in Mammalian Cells but Does Not Affect Virion Yield in Insect Cells

<b>Background/Objectives:</b> Baculoviruses represent promising gene delivery vectors for mammalian systems, combining high safety profiles with substantial cargo capacity. While pseudotyping with vesicular stomatitis virus G-protein (VSV-G) enhances transduction efficiency, optimal expr...

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Bibliographic Details
Main Authors: Jorge Alejandro Simonin, Franco Uriel Cuccovia Warlet, María del Rosario Bauzá, María del Pilar Plastine, Victoria Alfonso, Fernanda Daniela Olea, Carolina Susana Cerrudo, Mariano Nicolás Belaich
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Vaccines
Subjects:
baculovirus
AcMNPV
VSV-G
viral-based gene delivery
Online Access:https://www.mdpi.com/2076-393X/13/7/693
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