O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control
O-GlcNAcylation of intracellular proteins is a key regulator of diverse cellular and developmental processes. Previous studies have demonstrated the acute sensitivity of cell cycle progression to chemical and genetic manipulation of O-GlcNAc homeostasis. However, the mechanisms by which O-GlcNAc reg...
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Main Authors: | Conor W. Mitchell, Huijie Yuan, Marie Sønderstrup-Jensen, Andrew T. Ferenbach, Daan M. F. van Aalten |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2025-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.250064 |
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