Stroke and associated comorbidities in Southeast Asian countries

Abstract Stroke, a leading cause of mortality and morbidity worldwide, is a complex cerebrovascular disease. Stroke risk factors are diverse, encompassing age, sex, and ethnicity. Comorbid conditions, including hypertension, hyperglycemia, hyperlipidemia, and atrial fibrillation, exacerbate stroke o...

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Main Authors: Aishika Datta, Soumya Akundi, Kaveri Wagh, Gangadhar Bhurle, Deepaneeta Sarmah, Arvind Sharma, Sudhir Shah, Anupom Borah, Shailendra Saraf, Pallab Bhattacharya
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Neuroprotection
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Online Access:https://doi.org/10.1002/nep3.71
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author Aishika Datta
Soumya Akundi
Kaveri Wagh
Gangadhar Bhurle
Deepaneeta Sarmah
Arvind Sharma
Sudhir Shah
Anupom Borah
Shailendra Saraf
Pallab Bhattacharya
author_facet Aishika Datta
Soumya Akundi
Kaveri Wagh
Gangadhar Bhurle
Deepaneeta Sarmah
Arvind Sharma
Sudhir Shah
Anupom Borah
Shailendra Saraf
Pallab Bhattacharya
author_sort Aishika Datta
collection DOAJ
description Abstract Stroke, a leading cause of mortality and morbidity worldwide, is a complex cerebrovascular disease. Stroke risk factors are diverse, encompassing age, sex, and ethnicity. Comorbid conditions, including hypertension, hyperglycemia, hyperlipidemia, and atrial fibrillation, exacerbate stroke outcomes, contributing to the overall stroke burden within populations. In addition to these factors, lifestyle‐related diseases can impact individuals across all age groups, and often include as comorbidities linked to stroke. Socioeconomic conditions, healthcare access, and the quality of clinical data significantly influence the prevalence of comorbidities. Asia, the largest continent and home to 60% of the world's population, includes many developing nations undergoing diverse economic transitions. In Southeast Asian countries, stroke prevalence is high, imposing a substantial burden on healthcare systems and economies. Research disparities in stroke are often attributed to insufficient demographic data on comorbidities. Hence, the review discusses all previously published results of hospital‐based studies and data from national registries. It has been noticed that due to insufficient documentation on stroke‐related comorbidities in various developing countries of Southeast Asia, stroke management becomes difficult. Therefore, this review aims to discuss the association between various comorbidities and stroke, with special emphasis on the incidence and prevalence of stroke burden in Southeast Asian countries.
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spelling doaj-art-a8563a32b69a46e5b0cbbb30cece7ce42025-07-16T14:40:42ZengWileyNeuroprotection2770-72962770-730X2025-03-0131294710.1002/nep3.71Stroke and associated comorbidities in Southeast Asian countriesAishika Datta0Soumya Akundi1Kaveri Wagh2Gangadhar Bhurle3Deepaneeta Sarmah4Arvind Sharma5Sudhir Shah6Anupom Borah7Shailendra Saraf8Pallab Bhattacharya9Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat IndiaDepartment of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat IndiaDepartment of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat IndiaDepartment of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat IndiaDepartment of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat IndiaDepartment of Neurology Zydus Hospital Ahmedabad Gujarat IndiaDepartment of Neurology SVPIMSR and NHL Municipal Medical College & Sterling Hospital Ahmedabad Gujarat IndiaCellular and Molecular Neurobiology Laboratory, Department of Life Science and Bioinformatics Assam University Silchar Assam IndiaDepartment of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat IndiaDepartment of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad Gandhinagar Gujarat IndiaAbstract Stroke, a leading cause of mortality and morbidity worldwide, is a complex cerebrovascular disease. Stroke risk factors are diverse, encompassing age, sex, and ethnicity. Comorbid conditions, including hypertension, hyperglycemia, hyperlipidemia, and atrial fibrillation, exacerbate stroke outcomes, contributing to the overall stroke burden within populations. In addition to these factors, lifestyle‐related diseases can impact individuals across all age groups, and often include as comorbidities linked to stroke. Socioeconomic conditions, healthcare access, and the quality of clinical data significantly influence the prevalence of comorbidities. Asia, the largest continent and home to 60% of the world's population, includes many developing nations undergoing diverse economic transitions. In Southeast Asian countries, stroke prevalence is high, imposing a substantial burden on healthcare systems and economies. Research disparities in stroke are often attributed to insufficient demographic data on comorbidities. Hence, the review discusses all previously published results of hospital‐based studies and data from national registries. It has been noticed that due to insufficient documentation on stroke‐related comorbidities in various developing countries of Southeast Asia, stroke management becomes difficult. Therefore, this review aims to discuss the association between various comorbidities and stroke, with special emphasis on the incidence and prevalence of stroke burden in Southeast Asian countries.https://doi.org/10.1002/nep3.71comorbiditieshemorrhageincidenceischemiaprevalencestroke
spellingShingle Aishika Datta
Soumya Akundi
Kaveri Wagh
Gangadhar Bhurle
Deepaneeta Sarmah
Arvind Sharma
Sudhir Shah
Anupom Borah
Shailendra Saraf
Pallab Bhattacharya
Stroke and associated comorbidities in Southeast Asian countries
Neuroprotection
comorbidities
hemorrhage
incidence
ischemia
prevalence
stroke
title Stroke and associated comorbidities in Southeast Asian countries
title_full Stroke and associated comorbidities in Southeast Asian countries
title_fullStr Stroke and associated comorbidities in Southeast Asian countries
title_full_unstemmed Stroke and associated comorbidities in Southeast Asian countries
title_short Stroke and associated comorbidities in Southeast Asian countries
title_sort stroke and associated comorbidities in southeast asian countries
topic comorbidities
hemorrhage
incidence
ischemia
prevalence
stroke
url https://doi.org/10.1002/nep3.71
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