A genetic safeguard for eliminating target genes in synthetic probiotics in a gut environment
Summary: To meet the emerging demand for constraining engineered probiotic activities, many biocontainment studies explore strategies that involve killing engineered microbes, which often create basal levels of cytotoxicity that hamper cell fitness and performance. Here, we explored a circuit design...
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Main Authors: | Nhu Nguyen, Miaomiao Wang, Lin Li, Clement T.Y. Chan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-08-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422501288X |
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