Reconsideration on the value of biomaterials in the treatment of anal fistulas

The implantation of biomaterials to fill fistula tracts is a significant method for preserving the sphincter during anal fistula surgery. Procedures such as anal fistula plug implantation and BioLIFT have shown good results over the past 20 years. However, recent clinical outcomes have been less sat...

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Main Authors: Cao Jiawei, Lu Meijuan, Su Dan, Xiang Xiaoqiang, Zhu Peixuan, Ren Donglin
Format: Article
Language:Chinese
Published: Editorial Office of Journal of Colorectal & Anal Surgery 2022-12-01
Series:结直肠肛门外科
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Online Access:https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=320&cateName=2022%E5%B9%B4%20%E7%AC%AC28%E5%8D%B7%20%E7%AC%AC6%E6%9C%9F
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author Cao Jiawei
Lu Meijuan
Su Dan
Xiang Xiaoqiang
Zhu Peixuan
Ren Donglin
author_facet Cao Jiawei
Lu Meijuan
Su Dan
Xiang Xiaoqiang
Zhu Peixuan
Ren Donglin
author_sort Cao Jiawei
collection DOAJ
description The implantation of biomaterials to fill fistula tracts is a significant method for preserving the sphincter during anal fistula surgery. Procedures such as anal fistula plug implantation and BioLIFT have shown good results over the past 20 years. However, recent clinical outcomes have been less satisfactory, with a cure rate of less than 50% and high economic costs, leading many guidelines to not recommend biomaterial implantation as a first-line treatment for anal fistulas. Given the demand for sphincter-preserving techniques in various scenarios, surgeons are re-evaluating the scientific basis of using biomaterials to promote fistula healing. Is there an inherent superiority in the materials themselves? Are the variations in cure rates related to differences in indications, surgical techniques, postoperative care, and other factors? This paper systematically reviews and analyzes these issues.
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institution Matheson Library
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publishDate 2022-12-01
publisher Editorial Office of Journal of Colorectal & Anal Surgery
record_format Article
series 结直肠肛门外科
spelling doaj-art-a7f3d8ab40b1496e9e396c94d99e87c62025-07-03T02:12:39ZzhoEditorial Office of Journal of Colorectal & Anal Surgery结直肠肛门外科1674-04912022-12-0128654154610.19668/j.cnki.issn1674-0491.2022.06.004Reconsideration on the value of biomaterials in the treatment of anal fistulasCao Jiawei0Lu Meijuan1Su Dan2Xiang Xiaoqiang3Zhu Peixuan4Ren Donglin5Department of Anorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, ChinaQianhai Life Guangzhou General Hospital, Guangzhou, Guangdong 511325, ChinaDepartment of Anorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, ChinaShaanxi Provincial Medical Device Association, Xi'an, Shaanxi 710076, ChinaQianhai Life Guangzhou General Hospital, Guangzhou, Guangdong 511325, ChinaDepartment of Anorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, ChinaThe implantation of biomaterials to fill fistula tracts is a significant method for preserving the sphincter during anal fistula surgery. Procedures such as anal fistula plug implantation and BioLIFT have shown good results over the past 20 years. However, recent clinical outcomes have been less satisfactory, with a cure rate of less than 50% and high economic costs, leading many guidelines to not recommend biomaterial implantation as a first-line treatment for anal fistulas. Given the demand for sphincter-preserving techniques in various scenarios, surgeons are re-evaluating the scientific basis of using biomaterials to promote fistula healing. Is there an inherent superiority in the materials themselves? Are the variations in cure rates related to differences in indications, surgical techniques, postoperative care, and other factors? This paper systematically reviews and analyzes these issues.https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=320&cateName=2022%E5%B9%B4%20%E7%AC%AC28%E5%8D%B7%20%E7%AC%AC6%E6%9C%9Fanal fistula plugbiomaterialsanal fistula surgery
spellingShingle Cao Jiawei
Lu Meijuan
Su Dan
Xiang Xiaoqiang
Zhu Peixuan
Ren Donglin
Reconsideration on the value of biomaterials in the treatment of anal fistulas
结直肠肛门外科
anal fistula plug
biomaterials
anal fistula surgery
title Reconsideration on the value of biomaterials in the treatment of anal fistulas
title_full Reconsideration on the value of biomaterials in the treatment of anal fistulas
title_fullStr Reconsideration on the value of biomaterials in the treatment of anal fistulas
title_full_unstemmed Reconsideration on the value of biomaterials in the treatment of anal fistulas
title_short Reconsideration on the value of biomaterials in the treatment of anal fistulas
title_sort reconsideration on the value of biomaterials in the treatment of anal fistulas
topic anal fistula plug
biomaterials
anal fistula surgery
url https://jcas.gxmuyfy.cn/cn/wqll/paper.html?id=320&cateName=2022%E5%B9%B4%20%E7%AC%AC28%E5%8D%B7%20%E7%AC%AC6%E6%9C%9F
work_keys_str_mv AT caojiawei reconsiderationonthevalueofbiomaterialsinthetreatmentofanalfistulas
AT lumeijuan reconsiderationonthevalueofbiomaterialsinthetreatmentofanalfistulas
AT sudan reconsiderationonthevalueofbiomaterialsinthetreatmentofanalfistulas
AT xiangxiaoqiang reconsiderationonthevalueofbiomaterialsinthetreatmentofanalfistulas
AT zhupeixuan reconsiderationonthevalueofbiomaterialsinthetreatmentofanalfistulas
AT rendonglin reconsiderationonthevalueofbiomaterialsinthetreatmentofanalfistulas