Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy
The levels of erythropoietin (EPO) in biological fluids were studied on 43 patients with diabetes mellitus type I and II who suffered from a variety of clinical manifestations of heavy proliferative diabetic retinopathy (PDR) which incuded stable PDR, 12 patients with rhegmatogenous retinal detachme...
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| Language: | Russian |
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Real Time Ltd
2018-10-01
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| Series: | Российский офтальмологический журнал |
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| Online Access: | https://roj.igb.ru/jour/article/view/27 |
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| author | V. V. Neroev O. V. Zaitseva Z. V. Kurchaeva O. S. Slepova |
| author_facet | V. V. Neroev O. V. Zaitseva Z. V. Kurchaeva O. S. Slepova |
| author_sort | V. V. Neroev |
| collection | DOAJ |
| description | The levels of erythropoietin (EPO) in biological fluids were studied on 43 patients with diabetes mellitus type I and II who suffered from a variety of clinical manifestations of heavy proliferative diabetic retinopathy (PDR) which incuded stable PDR, 12 patients with rhegmatogenous retinal detachment and 15 healthy individuals The correlation of EPO levels with the clinical features of heavy PDR was noted only at the local level (intravitreally). The highest intraocular levels of EPO were associated with severe features of the disease, abundant vascularizarion of fibroglial tissue, and intraoperative hemorrhagic complications, which corroborates the theory of active participation of locally secreted EPO in ocular neoangiogenesis, including the progression of PDR // Russian Ophthalmological Journal, 2016; 2: 55-60. doi: 10.21516/2072-0076-2016-9-2-55-60 . |
| format | Article |
| id | doaj-art-a7ed6d8f8fe944f09399f2717ac6ac2b |
| institution | Matheson Library |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| publishDate | 2018-10-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj-art-a7ed6d8f8fe944f09399f2717ac6ac2b2025-08-03T19:22:31ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602018-10-0192556010.21516/2072-0076-2016-9-2-55-6027Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathyV. V. Neroev0O. V. Zaitseva1Z. V. Kurchaeva2O. S. Slepova3Helmholtz Research Institute of Eye Diseases, Moscow, RussiaHelmholtz Research Institute of Eye Diseases, Moscow, RussiaHelmholtz Research Institute of Eye Diseases, Moscow, RussiaHelmholtz Research Institute of Eye Diseases, Moscow, RussiaThe levels of erythropoietin (EPO) in biological fluids were studied on 43 patients with diabetes mellitus type I and II who suffered from a variety of clinical manifestations of heavy proliferative diabetic retinopathy (PDR) which incuded stable PDR, 12 patients with rhegmatogenous retinal detachment and 15 healthy individuals The correlation of EPO levels with the clinical features of heavy PDR was noted only at the local level (intravitreally). The highest intraocular levels of EPO were associated with severe features of the disease, abundant vascularizarion of fibroglial tissue, and intraoperative hemorrhagic complications, which corroborates the theory of active participation of locally secreted EPO in ocular neoangiogenesis, including the progression of PDR // Russian Ophthalmological Journal, 2016; 2: 55-60. doi: 10.21516/2072-0076-2016-9-2-55-60 .https://roj.igb.ru/jour/article/view/27пролиферативная диабетическая ретинопатияпатогенезхирургическое лечениеэритропоэтинproliferative diabetic retinopathypathogenesissurgical treatmenterythropoietin |
| spellingShingle | V. V. Neroev O. V. Zaitseva Z. V. Kurchaeva O. S. Slepova Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy Российский офтальмологический журнал пролиферативная диабетическая ретинопатия патогенез хирургическое лечение эритропоэтин proliferative diabetic retinopathy pathogenesis surgical treatment erythropoietin |
| title | Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy |
| title_full | Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy |
| title_fullStr | Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy |
| title_full_unstemmed | Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy |
| title_short | Local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy |
| title_sort | local and systemic erythropoietin levels in complicated proliferative diabetic retinopathy |
| topic | пролиферативная диабетическая ретинопатия патогенез хирургическое лечение эритропоэтин proliferative diabetic retinopathy pathogenesis surgical treatment erythropoietin |
| url | https://roj.igb.ru/jour/article/view/27 |
| work_keys_str_mv | AT vvneroev localandsystemicerythropoietinlevelsincomplicatedproliferativediabeticretinopathy AT ovzaitseva localandsystemicerythropoietinlevelsincomplicatedproliferativediabeticretinopathy AT zvkurchaeva localandsystemicerythropoietinlevelsincomplicatedproliferativediabeticretinopathy AT osslepova localandsystemicerythropoietinlevelsincomplicatedproliferativediabeticretinopathy |