The association of adolescent obesity with elevation of ESR: Which comes first?
Background: Obesity has become a global epidemic. Several studies suggest that adipose tissue is not only an inert energy store but also an endocrine organ that communicates with the central nervous system. Objective: To assess the association between erythrocyte sedimentation rate (ESR) and body ma...
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Elsevier
2025-12-01
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| Series: | Endocrine and Metabolic Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666396125000470 |
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| author | Sama Atta Gitti Saman SarKo Baha Al-den |
| author_facet | Sama Atta Gitti Saman SarKo Baha Al-den |
| author_sort | Sama Atta Gitti |
| collection | DOAJ |
| description | Background: Obesity has become a global epidemic. Several studies suggest that adipose tissue is not only an inert energy store but also an endocrine organ that communicates with the central nervous system. Objective: To assess the association between erythrocyte sedimentation rate (ESR) and body mass index (BMI), age, presence of complications such as diabetes and fatty liver disease, and weight loss. Methods: Fifty patients visited AL-Kindy specialized endocrinology outpatient clinic for obesity assessment. Patients were followed up for three months, and their baseline characteristics were analyzed using Student's t-test and chi-square test; p values <0.005 were considered significant. Results: The highest ESR values were observed in the age group of 10–14 years (mean ESR: 56.4 mm/h), followed by the 15–19 year group (mean ESR: 51.7 mm/h). The mean ESR in male patients was significantly higher than that in female patients (53.09 mm/h vs. 25.71 mm/h). Approximately 80 % of the patients with fatty liver disease had a high ESR. The patients were prescribed a calorie-restricted diet for three months; the mean BMI at the end of the study was 31.25 ± 1.21 kg/m2, and the mean ESR was 20.32 ± 30.2 mm/h compared with the baseline ESR of 35.8 ± 42.5 mm/h. Conclusion: The study findings indicate that a higher BMI is associated with higher ESR levels. The highest ESR values were observed in the age group of 10–14 years (mean 56.4 mm/h), suggesting that systemic inflammation may precede or accelerate the development of obesity during adolescence. |
| format | Article |
| id | doaj-art-a7c03a8f15d04785b9a1d44c7bf9cda8 |
| institution | Matheson Library |
| issn | 2666-3961 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Elsevier |
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| series | Endocrine and Metabolic Science |
| spelling | doaj-art-a7c03a8f15d04785b9a1d44c7bf9cda82025-07-15T04:16:24ZengElsevierEndocrine and Metabolic Science2666-39612025-12-0119100261The association of adolescent obesity with elevation of ESR: Which comes first?Sama Atta Gitti0Saman SarKo Baha Al-den1Corresponding author.; University of Baghdad, Al-Kindy College of Medicine, Iraq, BaghdadUniversity of Baghdad, Al-Kindy College of Medicine, Iraq, BaghdadBackground: Obesity has become a global epidemic. Several studies suggest that adipose tissue is not only an inert energy store but also an endocrine organ that communicates with the central nervous system. Objective: To assess the association between erythrocyte sedimentation rate (ESR) and body mass index (BMI), age, presence of complications such as diabetes and fatty liver disease, and weight loss. Methods: Fifty patients visited AL-Kindy specialized endocrinology outpatient clinic for obesity assessment. Patients were followed up for three months, and their baseline characteristics were analyzed using Student's t-test and chi-square test; p values <0.005 were considered significant. Results: The highest ESR values were observed in the age group of 10–14 years (mean ESR: 56.4 mm/h), followed by the 15–19 year group (mean ESR: 51.7 mm/h). The mean ESR in male patients was significantly higher than that in female patients (53.09 mm/h vs. 25.71 mm/h). Approximately 80 % of the patients with fatty liver disease had a high ESR. The patients were prescribed a calorie-restricted diet for three months; the mean BMI at the end of the study was 31.25 ± 1.21 kg/m2, and the mean ESR was 20.32 ± 30.2 mm/h compared with the baseline ESR of 35.8 ± 42.5 mm/h. Conclusion: The study findings indicate that a higher BMI is associated with higher ESR levels. The highest ESR values were observed in the age group of 10–14 years (mean 56.4 mm/h), suggesting that systemic inflammation may precede or accelerate the development of obesity during adolescence.http://www.sciencedirect.com/science/article/pii/S2666396125000470ObesityErythrocyte sedimentation rateInflammation |
| spellingShingle | Sama Atta Gitti Saman SarKo Baha Al-den The association of adolescent obesity with elevation of ESR: Which comes first? Endocrine and Metabolic Science Obesity Erythrocyte sedimentation rate Inflammation |
| title | The association of adolescent obesity with elevation of ESR: Which comes first? |
| title_full | The association of adolescent obesity with elevation of ESR: Which comes first? |
| title_fullStr | The association of adolescent obesity with elevation of ESR: Which comes first? |
| title_full_unstemmed | The association of adolescent obesity with elevation of ESR: Which comes first? |
| title_short | The association of adolescent obesity with elevation of ESR: Which comes first? |
| title_sort | association of adolescent obesity with elevation of esr which comes first |
| topic | Obesity Erythrocyte sedimentation rate Inflammation |
| url | http://www.sciencedirect.com/science/article/pii/S2666396125000470 |
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