The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion
The concept and pathological diagnostic criteria of gastric adenoma (dysplasia) differ between Western countries and Japan, and discrepancies between histopathological examinations before and after endoscopic resection may occur. Therefore, the natural history of adenoma should be interpreted and th...
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Korean College of Helicobacter and Upper Gastrointestinal Research
2018-06-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.2.103 |
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| author | Soo In Choi Jun Chul Park |
| author_facet | Soo In Choi Jun Chul Park |
| author_sort | Soo In Choi |
| collection | DOAJ |
| description | The concept and pathological diagnostic criteria of gastric adenoma (dysplasia) differ between Western countries and Japan, and discrepancies between histopathological examinations before and after endoscopic resection may occur. Therefore, the natural history of adenoma should be interpreted and the treatment strategy of adenoma established. It is recommended that endoscopic resection be performed for high-grade dysplasia due to the potential higher risk of progression to carcinoma. For low-grade dysplasia, the risk of malignant transformation is relatively low. However, resection is considered the first approach for the purpose of diagnosis and treatment. If resection is not feasible, the alternative may be to use argon plasma coagulation for selected lesions that are less likely to be malignant. When Helicobacter pylori infection is detected, eradication therapy is recommended to reduce the risk of metachronous lesions. Post-resection follow-up should be performed within 1 year to detect synchronous lesions and then follow-up endoscopy at 1 or 2-year intervals may be considered for metachronous lesions. |
| format | Article |
| id | doaj-art-a70eccf10b9c40b8b7dfbaf897412a3e |
| institution | Matheson Library |
| issn | 1738-3331 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-a70eccf10b9c40b8b7dfbaf897412a3e2025-08-02T16:00:22ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312018-06-0118210310910.7704/kjhugr.2018.18.2.103kjhugr.2018.18.2.103The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous LesionSoo In Choi0Jun Chul Park1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, KoreaDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, KoreaThe concept and pathological diagnostic criteria of gastric adenoma (dysplasia) differ between Western countries and Japan, and discrepancies between histopathological examinations before and after endoscopic resection may occur. Therefore, the natural history of adenoma should be interpreted and the treatment strategy of adenoma established. It is recommended that endoscopic resection be performed for high-grade dysplasia due to the potential higher risk of progression to carcinoma. For low-grade dysplasia, the risk of malignant transformation is relatively low. However, resection is considered the first approach for the purpose of diagnosis and treatment. If resection is not feasible, the alternative may be to use argon plasma coagulation for selected lesions that are less likely to be malignant. When Helicobacter pylori infection is detected, eradication therapy is recommended to reduce the risk of metachronous lesions. Post-resection follow-up should be performed within 1 year to detect synchronous lesions and then follow-up endoscopy at 1 or 2-year intervals may be considered for metachronous lesions.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.2.103AdenomaDysplasiaNatural historyStomachTreatment |
| spellingShingle | Soo In Choi Jun Chul Park The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion The Korean Journal of Helicobacter and Upper Gastrointestinal Research Adenoma Dysplasia Natural history Stomach Treatment |
| title | The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion |
| title_full | The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion |
| title_fullStr | The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion |
| title_full_unstemmed | The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion |
| title_short | The Natural History and Treatment Strategy of Gastric Adenoma as a Pre-cancerous Lesion |
| title_sort | natural history and treatment strategy of gastric adenoma as a pre cancerous lesion |
| topic | Adenoma Dysplasia Natural history Stomach Treatment |
| url | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.2.103 |
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