Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology

Purpose of the study. Studying possible management of postoperative pain and normalization of adaptation status in patients with reproductive system onychopathology using xenon- oxygen therapy.Patients and methods. The study included 97 patients receiving surgical treatment for reproductive cancer a...

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Main Authors: D. A. Rozenko, A. I. Shikhlyarova, N. N. Popova, E. V. Verenikina, A. P. Menshenina, A. Yu. Ardzha, A. V. Shulga
Format: Article
Language:Russian
Published: ANO "Perspective of oncology" 2021-03-01
Series:Южно-Российский онкологический журнал
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Online Access:https://www.cancersp.com/jour/article/view/103
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author D. A. Rozenko
A. I. Shikhlyarova
N. N. Popova
E. V. Verenikina
A. P. Menshenina
A. Yu. Ardzha
A. V. Shulga
author_facet D. A. Rozenko
A. I. Shikhlyarova
N. N. Popova
E. V. Verenikina
A. P. Menshenina
A. Yu. Ardzha
A. V. Shulga
author_sort D. A. Rozenko
collection DOAJ
description Purpose of the study. Studying possible management of postoperative pain and normalization of adaptation status in patients with reproductive system onychopathology using xenon- oxygen therapy.Patients and methods. The study included 97 patients receiving surgical treatment for reproductive cancer at National Medical Research Centre for Oncology in 2016–2020. All patients were divided into the main and control groups depending on the performed corrective therapy with xenon- oxygen mixture. Inclusion criteria were: established diagnosis — endometrial cancer, cervical cancer or ovarian cancer at the surgical stage of antitumor treatment, absence of decompensated concomitant pathology. In addition to general clinical tests, the intensity of symptoms in patients was assessed using a standardized Edmonton questionnaire, adaptation status and data of a numerical rating scale of pain were recorded, the severity of endogenous intoxication was measured using calculated lymphocytic, leukocyte, nuclear and leukocyte shift index. Stages of the study included functional assessment of the patient's condition before surgical treatment and on the 1st and 5th days of the postoperative period.Results. An analysis showed statistically significant differences between the groups: in the group of patients receiving xenon- oxygen therapy, 12.9% of patients complained of pain, while in the control group — 34.2%, on mild exertion 17.1% and 39.9%, respectively (p<0.05). The therapy with xenon- oxygen mixture demonstrated its high significance in the adaptive status regulation and regression of negative clinical manifestations in patients after oncogynecological surgeries.Conclusion. The effectiveness of the chosen therapy with xenon- oxygen mixture demonstrates the possibility of anesthesia and normalization of the adaptive status of oncogynecological patients who underwent surgical treatment for reproductive cancers.
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spelling doaj-art-a6f15b29befe4fbd902cd2d89aa42dcb2025-08-03T13:06:49ZrusANO "Perspective of oncology"Южно-Российский онкологический журнал2686-90392021-03-0121142510.37748/2686-9039-2021-2-1-230Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathologyD. A. Rozenko0A. I. Shikhlyarova1N. N. Popova2E. V. Verenikina3A. P. Menshenina4A. Yu. Ardzha5A. V. Shulga6National Medical Research Centre for Oncology of the Ministry of Health of RussiaNational Medical Research Centre for Oncology of the Ministry of Health of RussiaNational Medical Research Centre for Oncology of the Ministry of Health of Russia; Rostov State Medical UniversityNational Medical Research Centre for Oncology of the Ministry of Health of RussiaNational Medical Research Centre for Oncology of the Ministry of Health of RussiaNational Medical Research Centre for Oncology of the Ministry of Health of Russia; Rostov State Medical UniversityNational Medical Research Centre for Oncology of the Ministry of Health of RussiaPurpose of the study. Studying possible management of postoperative pain and normalization of adaptation status in patients with reproductive system onychopathology using xenon- oxygen therapy.Patients and methods. The study included 97 patients receiving surgical treatment for reproductive cancer at National Medical Research Centre for Oncology in 2016–2020. All patients were divided into the main and control groups depending on the performed corrective therapy with xenon- oxygen mixture. Inclusion criteria were: established diagnosis — endometrial cancer, cervical cancer or ovarian cancer at the surgical stage of antitumor treatment, absence of decompensated concomitant pathology. In addition to general clinical tests, the intensity of symptoms in patients was assessed using a standardized Edmonton questionnaire, adaptation status and data of a numerical rating scale of pain were recorded, the severity of endogenous intoxication was measured using calculated lymphocytic, leukocyte, nuclear and leukocyte shift index. Stages of the study included functional assessment of the patient's condition before surgical treatment and on the 1st and 5th days of the postoperative period.Results. An analysis showed statistically significant differences between the groups: in the group of patients receiving xenon- oxygen therapy, 12.9% of patients complained of pain, while in the control group — 34.2%, on mild exertion 17.1% and 39.9%, respectively (p<0.05). The therapy with xenon- oxygen mixture demonstrated its high significance in the adaptive status regulation and regression of negative clinical manifestations in patients after oncogynecological surgeries.Conclusion. The effectiveness of the chosen therapy with xenon- oxygen mixture demonstrates the possibility of anesthesia and normalization of the adaptive status of oncogynecological patients who underwent surgical treatment for reproductive cancers.https://www.cancersp.com/jour/article/view/103reproductive cancerspostoperative painxenon-oxygen therapyadaptation statuspsychological statusrehabilitation treatment
spellingShingle D. A. Rozenko
A. I. Shikhlyarova
N. N. Popova
E. V. Verenikina
A. P. Menshenina
A. Yu. Ardzha
A. V. Shulga
Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology
Южно-Российский онкологический журнал
reproductive cancers
postoperative pain
xenon-oxygen therapy
adaptation status
psychological status
rehabilitation treatment
title Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology
title_full Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology
title_fullStr Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology
title_full_unstemmed Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology
title_short Efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology
title_sort efficiency mark postoperative pain management and normalization of adaptation status in patients with reproductive system oncopathology
topic reproductive cancers
postoperative pain
xenon-oxygen therapy
adaptation status
psychological status
rehabilitation treatment
url https://www.cancersp.com/jour/article/view/103
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AT nnpopova efficiencymarkpostoperativepainmanagementandnormalizationofadaptationstatusinpatientswithreproductivesystemoncopathology
AT evverenikina efficiencymarkpostoperativepainmanagementandnormalizationofadaptationstatusinpatientswithreproductivesystemoncopathology
AT apmenshenina efficiencymarkpostoperativepainmanagementandnormalizationofadaptationstatusinpatientswithreproductivesystemoncopathology
AT ayuardzha efficiencymarkpostoperativepainmanagementandnormalizationofadaptationstatusinpatientswithreproductivesystemoncopathology
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