СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1
Chronic cerebrovascular attack (CCVA) is a brain lesion caused by vascular factors. CCVA appears as cognitive impairments (CI), affective (emotional) disorders and focal syndromes. Treatment for CCVA requires a comprehensive approach. Combination effective therapy for CCVA involves secondary prevent...
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SINAPS LLC
2014-06-01
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| Series: | Архивъ внутренней медицины |
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| Online Access: | https://www.medarhive.ru/jour/article/view/294 |
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| author | А. А. Шмонин В. С. Краснов И. А. Шмонина Е. В. Мельникова |
| author_facet | А. А. Шмонин В. С. Краснов И. А. Шмонина Е. В. Мельникова |
| author_sort | А. А. Шмонин |
| collection | DOAJ |
| description | Chronic cerebrovascular attack (CCVA) is a brain lesion caused by vascular factors. CCVA appears as cognitive impairments (CI), affective (emotional) disorders and focal syndromes. Treatment for CCVA requires a comprehensive approach. Combination effective therapy for CCVA involves secondary prevention of stroke and CI; treatment of CI; treatment of depression and other affective disorders; neuroprotective therapy. Basic therapy for CCVA includes modification of risk factors, antihypertensive, hypolipidemic, and antithrombotic therapies. Central acetylcholinesterase inhibitors (galantamine, rivastigmine, donepezil) and a reversible NMDA receptor blocker (memantine) are symptomatically used at a stage of vascular and mixed dementia. There are no unique guidelines for the therapy of mild and moderate vascular nondementia-related CI. Drug use, based on the neurochemical mechanisms underlying the development of vascular CI, is substantiated. When choosing psychotropic agents, it is necessary to take into account the causes and clinical manifestations of neuromediator deficiency. Antidepressants are used as essential drugs. Neuroleptics and tranquilizers are additionally administered in complex-pattern syndromes, such as depression with marked anxiety. Prescription of neuroprotectors may be effective in treating both stroke and CCVA. These medicaments are most effective when a damaging factor acts, i.e. neuroprotectors should be given in a risk situation and to reduce damage. Citicoline is one of the most test drugs in a group of neuroprotectors. |
| format | Article |
| id | doaj-art-a6cae6d2c49b4c71b3674f186d1ee51a |
| institution | Matheson Library |
| issn | 2226-6704 2411-6564 |
| language | Russian |
| publishDate | 2014-06-01 |
| publisher | SINAPS LLC |
| record_format | Article |
| series | Архивъ внутренней медицины |
| spelling | doaj-art-a6cae6d2c49b4c71b3674f186d1ee51a2025-08-04T14:09:43ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642014-06-0103121710.20514/2226-6704-2014-0-3-12-17307СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1А. А. Шмонин0В. С. Краснов1И. А. Шмонина2Е. В. Мельникова3ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова»; ФГБУ «Федеральный медицинский исследовательский центр им. В.А. Алмазова»ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова»ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова»; ФГБУ «Федеральный медицинский исследовательский центр им. В.А. Алмазова»ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова»Chronic cerebrovascular attack (CCVA) is a brain lesion caused by vascular factors. CCVA appears as cognitive impairments (CI), affective (emotional) disorders and focal syndromes. Treatment for CCVA requires a comprehensive approach. Combination effective therapy for CCVA involves secondary prevention of stroke and CI; treatment of CI; treatment of depression and other affective disorders; neuroprotective therapy. Basic therapy for CCVA includes modification of risk factors, antihypertensive, hypolipidemic, and antithrombotic therapies. Central acetylcholinesterase inhibitors (galantamine, rivastigmine, donepezil) and a reversible NMDA receptor blocker (memantine) are symptomatically used at a stage of vascular and mixed dementia. There are no unique guidelines for the therapy of mild and moderate vascular nondementia-related CI. Drug use, based on the neurochemical mechanisms underlying the development of vascular CI, is substantiated. When choosing psychotropic agents, it is necessary to take into account the causes and clinical manifestations of neuromediator deficiency. Antidepressants are used as essential drugs. Neuroleptics and tranquilizers are additionally administered in complex-pattern syndromes, such as depression with marked anxiety. Prescription of neuroprotectors may be effective in treating both stroke and CCVA. These medicaments are most effective when a damaging factor acts, i.e. neuroprotectors should be given in a risk situation and to reduce damage. Citicoline is one of the most test drugs in a group of neuroprotectors.https://www.medarhive.ru/jour/article/view/294chronic cerebrovascular attackaffective (emotional) disorderspathogenesissecondary preventionneuroprotective therapy |
| spellingShingle | А. А. Шмонин В. С. Краснов И. А. Шмонина Е. В. Мельникова СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1 Архивъ внутренней медицины chronic cerebrovascular attack affective (emotional) disorders pathogenesis secondary prevention neuroprotective therapy |
| title | СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1 |
| title_full | СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1 |
| title_fullStr | СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1 |
| title_full_unstemmed | СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1 |
| title_short | СОВРЕМЕННАЯ ТЕРАПИЯ ХРОНИЧЕСКОГО НАРУШЕНИЯ МОЗГОВОГО КРОВООБРАЩЕНИЯ. Часть 1 |
| title_sort | современная терапия хронического нарушения мозгового кровообращения часть 1 |
| topic | chronic cerebrovascular attack affective (emotional) disorders pathogenesis secondary prevention neuroprotective therapy |
| url | https://www.medarhive.ru/jour/article/view/294 |
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