Curcumin exerts protective effects against doxorubicin-induced cardiotoxicity

Curcumin exerts protective effects against doxorubicin-induced cardiotoxicity

The mechanism of doxorubicin (Dox) cardiotoxicity involves different pathways, including oxidative stress and mitochondrial dysfunction. It’s supposed that pharmacological effect on HIF gene expression may protect the heart against the detrimental effects of the doxorubicin-induced injury. We hypoth...

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Bibliographic Details
Main Authors: O. О. Klymenko, T. I. Drevytska, O. O. Gonchar, K. V. Tarasova, V. I. Nosar, V. Ye. Dosenko, I. M. Mankovska
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2025-02-01
Series:The Ukrainian Biochemical Journal
Subjects:
cardiomyocyte
curcumin
doxorubicin
expression of hif subunits
membrane potential
mitochondria
oxidative stress
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2025/02/Klymenko_97_1.pdf
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