Atrial cardiomyopathy — a new concept with a long history
Atrial cardiomyopathy (ACM) is a relatively common but clinically underestimated disorder, which is characterized by an increased atrial size and dysfunction. Previously, ACM was considered a primary disorder, but in 2016 this concept was revised by European Heart Rhythm Association (EHRA) working g...
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Format: | Article |
Language: | Russian |
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«FIRMA «SILICEA» LLC
2020-12-01
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Series: | Российский кардиологический журнал |
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Online Access: | https://russjcardiol.elpub.ru/jour/article/view/3942 |
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author | T. G. Vaikhanskaya T. V. Kurushko Yu. A. Persianskikh L. N. Sivitskaya |
author_facet | T. G. Vaikhanskaya T. V. Kurushko Yu. A. Persianskikh L. N. Sivitskaya |
author_sort | T. G. Vaikhanskaya |
collection | DOAJ |
description | Atrial cardiomyopathy (ACM) is a relatively common but clinically underestimated disorder, which is characterized by an increased atrial size and dysfunction. Previously, ACM was considered a primary disorder, but in 2016 this concept was revised by European Heart Rhythm Association (EHRA) working group with inclusion of secondary atrial remodeling. The EHRA document details aspects of atrial anatomy and pathophysiology, proposes definitions of ACM, histological classification, outlines the molecular mechanisms of atrial arrhythmia and the problems of personalized treatment and optimization of indications for catheter ablation.Practical application of the proposed ACM classification system, the clinical significance of novel ACM concept and the potential role of this information for a practitioner are presented in this article. Two clinical cases of ACM with “primary” (familial form of ACM due to NPPA gene mutation with primary defect in atrial structure and function) and “secondary” atrial remodeling (ACM caused by a longterm supraventricular tachyarrhythmias due to SCN1B gene mutation). |
format | Article |
id | doaj-art-a64e2f9f3c834719a3c573003c0034b1 |
institution | Matheson Library |
issn | 1560-4071 2618-7620 |
language | Russian |
publishDate | 2020-12-01 |
publisher | «FIRMA «SILICEA» LLC |
record_format | Article |
series | Российский кардиологический журнал |
spelling | doaj-art-a64e2f9f3c834719a3c573003c0034b12025-08-04T13:00:22Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202020-12-01251110.15829/29/1560-4071-2020-39422990Atrial cardiomyopathy — a new concept with a long historyT. G. Vaikhanskaya0T. V. Kurushko1Yu. A. Persianskikh2L. N. Sivitskaya3Republican Science-Practical Centre “Cardiology”Republican Science-Practical Centre “Cardiology”Republican Science-Practical Centre “Cardiology”Institute of Genetics and CytologyAtrial cardiomyopathy (ACM) is a relatively common but clinically underestimated disorder, which is characterized by an increased atrial size and dysfunction. Previously, ACM was considered a primary disorder, but in 2016 this concept was revised by European Heart Rhythm Association (EHRA) working group with inclusion of secondary atrial remodeling. The EHRA document details aspects of atrial anatomy and pathophysiology, proposes definitions of ACM, histological classification, outlines the molecular mechanisms of atrial arrhythmia and the problems of personalized treatment and optimization of indications for catheter ablation.Practical application of the proposed ACM classification system, the clinical significance of novel ACM concept and the potential role of this information for a practitioner are presented in this article. Two clinical cases of ACM with “primary” (familial form of ACM due to NPPA gene mutation with primary defect in atrial structure and function) and “secondary” atrial remodeling (ACM caused by a longterm supraventricular tachyarrhythmias due to SCN1B gene mutation).https://russjcardiol.elpub.ru/jour/article/view/3942atrial remodelingatrial cardiomyopathyatrial fibrillationatrial electromechanical dysfunction<i>nppa</i> gene |
spellingShingle | T. G. Vaikhanskaya T. V. Kurushko Yu. A. Persianskikh L. N. Sivitskaya Atrial cardiomyopathy — a new concept with a long history Российский кардиологический журнал atrial remodeling atrial cardiomyopathy atrial fibrillation atrial electromechanical dysfunction <i>nppa</i> gene |
title | Atrial cardiomyopathy — a new concept with a long history |
title_full | Atrial cardiomyopathy — a new concept with a long history |
title_fullStr | Atrial cardiomyopathy — a new concept with a long history |
title_full_unstemmed | Atrial cardiomyopathy — a new concept with a long history |
title_short | Atrial cardiomyopathy — a new concept with a long history |
title_sort | atrial cardiomyopathy a new concept with a long history |
topic | atrial remodeling atrial cardiomyopathy atrial fibrillation atrial electromechanical dysfunction <i>nppa</i> gene |
url | https://russjcardiol.elpub.ru/jour/article/view/3942 |
work_keys_str_mv | AT tgvaikhanskaya atrialcardiomyopathyanewconceptwithalonghistory AT tvkurushko atrialcardiomyopathyanewconceptwithalonghistory AT yuapersianskikh atrialcardiomyopathyanewconceptwithalonghistory AT lnsivitskaya atrialcardiomyopathyanewconceptwithalonghistory |