Effects of gender-affirming hormones on diurnal cortisol concentrations: A prospective study

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Effects of gender-affirming hormones on diurnal cortisol concentrations: A prospective study

The diurnal rhythm of the hypothalamic-pituitary-adrenal (HPA) axis is essential for physical and mental health. There are sex differences in this diurnal rhythm, including steeper diurnal cortisol slopes in females compared to males, and sex hormones likely contribute to this difference. While prev...

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Bibliographic Details
Main Authors:	Margot W.L. Morssinkhof, David Matthew Doyle, Ysbrand D. van der Werf, Martin den Heijer, Annemieke Heijboer, Birit F.P. Broekman, Dirk Jan Stenvers
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Series:	Neurobiology of Stress
Subjects:	Cortisol HPA axis Sex hormones Transgender Estradiol Testosterone
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352289525000359
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