Antibacterial Therapy of Tularemia: Current Status and Prospects
The review article includes summarized literature data on experimental evaluation of Francisella tularensis susceptibility to existing antibiotics, and their effectiveness in treatment of tularemia in humans population. The data on ways to improve the effectiveness of some antibacterial drugs that...
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Format: | Article |
Language: | Russian |
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LLC "Publishing House OKI"
2020-06-01
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Series: | Антибиотики и Химиотерапия |
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Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/721 |
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author | I. A. Shchipeleva E. I. Markovskaya O. F. Kretenchuk |
author_facet | I. A. Shchipeleva E. I. Markovskaya O. F. Kretenchuk |
author_sort | I. A. Shchipeleva |
collection | DOAJ |
description | The review article includes summarized literature data on experimental evaluation of Francisella tularensis susceptibility to existing antibiotics, and their effectiveness in treatment of tularemia in humans population. The data on ways to improve the effectiveness of some antibacterial drugs that show reduced activity in treatment of tularemia infection are presented. The range of studies aimed at creating modern and more effective antibiotics with new mechanisms of action is defined. A number of methods for modifying variants of the already known groups of antibacterial drugs, as well as ways of prevention or limitation of antibiotic resistance formation in F.tularensis are described. |
format | Article |
id | doaj-art-a4ff974494794ba3a74750029b51a1d1 |
institution | Matheson Library |
issn | 0235-2990 |
language | Russian |
publishDate | 2020-06-01 |
publisher | LLC "Publishing House OKI" |
record_format | Article |
series | Антибиотики и Химиотерапия |
spelling | doaj-art-a4ff974494794ba3a74750029b51a1d12025-08-03T13:04:48ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-06-01653-4394410.37489/0235-2990-2020-65-3-4-39-44719Antibacterial Therapy of Tularemia: Current Status and ProspectsI. A. Shchipeleva0E. I. Markovskaya1O. F. Kretenchuk2Rostov-on-Don Antiplague Scientific Research InstituteRostov-on-Don Antiplague Scientific Research InstituteRostov-on-Don Antiplague Scientific Research InstituteThe review article includes summarized literature data on experimental evaluation of Francisella tularensis susceptibility to existing antibiotics, and their effectiveness in treatment of tularemia in humans population. The data on ways to improve the effectiveness of some antibacterial drugs that show reduced activity in treatment of tularemia infection are presented. The range of studies aimed at creating modern and more effective antibiotics with new mechanisms of action is defined. A number of methods for modifying variants of the already known groups of antibacterial drugs, as well as ways of prevention or limitation of antibiotic resistance formation in F.tularensis are described.https://www.antibiotics-chemotherapy.ru/jour/article/view/721francisella tularensistularemiaantibioticstreatmentresistance |
spellingShingle | I. A. Shchipeleva E. I. Markovskaya O. F. Kretenchuk Antibacterial Therapy of Tularemia: Current Status and Prospects Антибиотики и Химиотерапия francisella tularensis tularemia antibiotics treatment resistance |
title | Antibacterial Therapy of Tularemia: Current Status and Prospects |
title_full | Antibacterial Therapy of Tularemia: Current Status and Prospects |
title_fullStr | Antibacterial Therapy of Tularemia: Current Status and Prospects |
title_full_unstemmed | Antibacterial Therapy of Tularemia: Current Status and Prospects |
title_short | Antibacterial Therapy of Tularemia: Current Status and Prospects |
title_sort | antibacterial therapy of tularemia current status and prospects |
topic | francisella tularensis tularemia antibiotics treatment resistance |
url | https://www.antibiotics-chemotherapy.ru/jour/article/view/721 |
work_keys_str_mv | AT iashchipeleva antibacterialtherapyoftularemiacurrentstatusandprospects AT eimarkovskaya antibacterialtherapyoftularemiacurrentstatusandprospects AT ofkretenchuk antibacterialtherapyoftularemiacurrentstatusandprospects |