Antibacterial Therapy of Tularemia: Current Status and Prospects

The review article includes summarized literature data on experimental evaluation of Francisella tularensis susceptibility to exist­ing antibiotics, and their effectiveness in treatment of tularemia in humans population. The data on ways to improve the effective­ness of some antibacterial drugs that...

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Main Authors: I. A. Shchipeleva, E. I. Markovskaya, O. F. Kretenchuk
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-06-01
Series:Антибиотики и Химиотерапия
Subjects:
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/721
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author I. A. Shchipeleva
E. I. Markovskaya
O. F. Kretenchuk
author_facet I. A. Shchipeleva
E. I. Markovskaya
O. F. Kretenchuk
author_sort I. A. Shchipeleva
collection DOAJ
description The review article includes summarized literature data on experimental evaluation of Francisella tularensis susceptibility to exist­ing antibiotics, and their effectiveness in treatment of tularemia in humans population. The data on ways to improve the effective­ness of some antibacterial drugs that show reduced activity in treatment of tularemia infection are presented. The range of studies aimed at creating modern and more effective antibiotics with new mechanisms of action is defined. A number of methods for mod­ifying variants of the already known groups of antibacterial drugs, as well as ways of prevention or limitation of antibiotic resist­ance formation in F.tularensis are described.
format Article
id doaj-art-a4ff974494794ba3a74750029b51a1d1
institution Matheson Library
issn 0235-2990
language Russian
publishDate 2020-06-01
publisher LLC "Publishing House OKI"
record_format Article
series Антибиотики и Химиотерапия
spelling doaj-art-a4ff974494794ba3a74750029b51a1d12025-08-03T13:04:48ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-06-01653-4394410.37489/0235-2990-2020-65-3-4-39-44719Antibacterial Therapy of Tularemia: Current Status and ProspectsI. A. Shchipeleva0E. I. Markovskaya1O. F. Kretenchuk2Rostov-on-Don Antiplague Scientific Research InstituteRostov-on-Don Antiplague Scientific Research InstituteRostov-on-Don Antiplague Scientific Research InstituteThe review article includes summarized literature data on experimental evaluation of Francisella tularensis susceptibility to exist­ing antibiotics, and their effectiveness in treatment of tularemia in humans population. The data on ways to improve the effective­ness of some antibacterial drugs that show reduced activity in treatment of tularemia infection are presented. The range of studies aimed at creating modern and more effective antibiotics with new mechanisms of action is defined. A number of methods for mod­ifying variants of the already known groups of antibacterial drugs, as well as ways of prevention or limitation of antibiotic resist­ance formation in F.tularensis are described.https://www.antibiotics-chemotherapy.ru/jour/article/view/721francisella tularensistularemiaantibioticstreatmentresistance
spellingShingle I. A. Shchipeleva
E. I. Markovskaya
O. F. Kretenchuk
Antibacterial Therapy of Tularemia: Current Status and Prospects
Антибиотики и Химиотерапия
francisella tularensis
tularemia
antibiotics
treatment
resistance
title Antibacterial Therapy of Tularemia: Current Status and Prospects
title_full Antibacterial Therapy of Tularemia: Current Status and Prospects
title_fullStr Antibacterial Therapy of Tularemia: Current Status and Prospects
title_full_unstemmed Antibacterial Therapy of Tularemia: Current Status and Prospects
title_short Antibacterial Therapy of Tularemia: Current Status and Prospects
title_sort antibacterial therapy of tularemia current status and prospects
topic francisella tularensis
tularemia
antibiotics
treatment
resistance
url https://www.antibiotics-chemotherapy.ru/jour/article/view/721
work_keys_str_mv AT iashchipeleva antibacterialtherapyoftularemiacurrentstatusandprospects
AT eimarkovskaya antibacterialtherapyoftularemiacurrentstatusandprospects
AT ofkretenchuk antibacterialtherapyoftularemiacurrentstatusandprospects