Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review
Inflammation is an essential part of the immune response to injury and infection. Emerging evidence indicates that long-term low-grade inflammation is positively correlated with many diseases, such as cancer, metabolic disorders, and cardiovascular diseases. Due to common anti-inflammatory drugs are...
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| Format: | Article |
| Language: | English |
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Compuscript Ltd
2023-08-01
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| Series: | Acta Materia Medica |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0026 |
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| author | Cheng Chen Zheling Feng Jovana Petrović Marina Soković Yang Ye Ligen Lin |
| author_facet | Cheng Chen Zheling Feng Jovana Petrović Marina Soković Yang Ye Ligen Lin |
| author_sort | Cheng Chen |
| collection | DOAJ |
| description | Inflammation is an essential part of the immune response to injury and infection. Emerging evidence indicates that long-term low-grade inflammation is positively correlated with many diseases, such as cancer, metabolic disorders, and cardiovascular diseases. Due to common anti-inflammatory drugs are suitable for treating acute inflammation and cause severe adverse effects, new safe and effective drug candidates are urgently needed for treating chronic inflammation. Plants of the Asteraceae family have been widely used in traditional medicines for relieving fever symptoms and killing pathogens. The anti-inflammatory properties of sesquiterpenoids from plants in the Asteraceae family have attracted increasing attention in recent decades because of their structural complexity and potent bioactivities. Herein, we provide a comprehensive and up-to-date summary of sesquiterpenoids from the Asteraceae family with anti-inflammatory properties, including their drug likeness and druggability, as analyzed with the SwissADME and ADMETlab online tools. In the future, some sesquiterpenoids might serve as therapeutic agents to treat inflammation-associated diseases. |
| format | Article |
| id | doaj-art-a4acbb916cd24bbfa4a071fee42f940c |
| institution | Matheson Library |
| issn | 2737-7946 |
| language | English |
| publishDate | 2023-08-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Acta Materia Medica |
| spelling | doaj-art-a4acbb916cd24bbfa4a071fee42f940c2025-06-27T16:00:18ZengCompuscript LtdActa Materia Medica2737-79462023-08-012335737610.15212/AMM-2023-0026Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a reviewCheng ChenZheling FengJovana PetrovićMarina SokovićYang YeLigen LinInflammation is an essential part of the immune response to injury and infection. Emerging evidence indicates that long-term low-grade inflammation is positively correlated with many diseases, such as cancer, metabolic disorders, and cardiovascular diseases. Due to common anti-inflammatory drugs are suitable for treating acute inflammation and cause severe adverse effects, new safe and effective drug candidates are urgently needed for treating chronic inflammation. Plants of the Asteraceae family have been widely used in traditional medicines for relieving fever symptoms and killing pathogens. The anti-inflammatory properties of sesquiterpenoids from plants in the Asteraceae family have attracted increasing attention in recent decades because of their structural complexity and potent bioactivities. Herein, we provide a comprehensive and up-to-date summary of sesquiterpenoids from the Asteraceae family with anti-inflammatory properties, including their drug likeness and druggability, as analyzed with the SwissADME and ADMETlab online tools. In the future, some sesquiterpenoids might serve as therapeutic agents to treat inflammation-associated diseases.https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0026 |
| spellingShingle | Cheng Chen Zheling Feng Jovana Petrović Marina Soković Yang Ye Ligen Lin Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review Acta Materia Medica |
| title | Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review |
| title_full | Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review |
| title_fullStr | Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review |
| title_full_unstemmed | Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review |
| title_short | Sesquiterpenoids from the sunflower family as potential anti-inflammatory candidates: a review |
| title_sort | sesquiterpenoids from the sunflower family as potential anti inflammatory candidates a review |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2023-0026 |
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