Association of Genetic Variants With Rivaroxaban Pharmacokinetics and Pharmacodynamics and Hemorrhage Risk Factors in Patients With Venous Thromboembolism
Background Rivaroxaban is a first‐line agent for venous thromboembolism prophylaxis and treatment. However, its pharmacokinetics, pharmacodynamics, and bleeding risk exhibit significant interindividual variability. Known nongenetic factors alone cannot fully explain this variability, and the impact...
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Main Authors: | Hui Li, Xiaoshuang He, Yingyun Guan, Qiuya Lu, Jie Fang, Xiaolan Bian |
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Format: | Article |
Language: | English |
Published: |
Wiley
2025-06-01
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Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
Subjects: | |
Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.040698 |
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