Functional efficiency of pancreatic cell-engineered construct in an animal experimental model for type I diabetes

Functional efficiency of pancreatic cell-engineered construct in an animal experimental model for type I diabetes

The creation of a cell-engineered pancreatic construct (CEPC) from islets of Langerhans and biocompatible matrix carrier (framework/scaffold), which imitates the native microenvironment of pancreatic tissue, is an approach to the treatment of type I diabetes mellitus (T1D).The objective of this work...

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Bibliographic Details
Main Authors: N. V. Baranova, A. S. Ponomareva, L. A. Kirsanova, A. O. Nikolskaya, G. N. Bubentsova, Yu. B. Basok, V. I. Sevastianov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2024-07-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
type i diabetes mellitus
islets of langerhans
cell-engineered construct
pancreas
decellularization, tissue-specific scaffold
Online Access:https://journal.transpl.ru/vtio/article/view/1772
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