Investigation of the morphofunctional status of macrophages in abdominal adhesions in rats and on exposure to oxidized dextran

Investigation of the morphofunctional status of macrophages in abdominal adhesions in rats and on exposure to oxidized dextran

Abdominal adhesions result from the organization of fibrinous exudate and subsequent fibrosis, attributed to the low phagocytic activity of macrophages associated with their M1 phenotype. Oxidized dextran (OD) can limit the development of fibrosis by exerting a stimulating effect on phagocytosis.The...

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Bibliographic Details
Main Authors: M. A. Karpov, A. P. Nadeev, V. A. Shkurupiy, N. P. Bgatova, A. V. Basova, M. A. Volchek, A. V. Volchek
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Siberian Branch Publishing House 2025-05-01
Series:Сибирский научный медицинский журнал
Subjects:
adhesions
rats
oxidized dextran
macrophages
polarization
ultrastructure
electron microscopy
Online Access:https://sibmed.elpub.ru/jour/article/view/2079
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