Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro)
The adhesion of Staphylococcus aureus ATCC® 25923 and the clinical strains of S.aureus, S.epidermidis on monofilament surgical mesh implants - macroporous polyester and microporous polypropylene in combination with biocides was assessed in an in vitro experiment. Staphylococcus cells adhered to the...
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| Format: | Article |
| Language: | Russian |
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LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
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| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/55 |
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| author | M. V. Kuznetsova A. A. Parshakov E. V. Afanasyevskaya V. A. Samartsev |
| author_facet | M. V. Kuznetsova A. A. Parshakov E. V. Afanasyevskaya V. A. Samartsev |
| author_sort | M. V. Kuznetsova |
| collection | DOAJ |
| description | The adhesion of Staphylococcus aureus ATCC® 25923 and the clinical strains of S.aureus, S.epidermidis on monofilament surgical mesh implants - macroporous polyester and microporous polypropylene in combination with biocides was assessed in an in vitro experiment. Staphylococcus cells adhered to the surface of implant fragments without treatment with biocides within a few hours, and there was no significant effect on the adhesion of the structure or chemical composition of the fiber. Short-term exposure of implants to the solutions of amoxiclav (100 μg/ml) and chlorhexidine (0.5%) led to inhibition of bacterial growth and contamination of the surface for at least two days. In the experiment with vancomycin (100 μg/ml), bacterial cells adhered on the surface of the mesh fragments after 24 h, but their amount was significantly lower than in the control group. It was noted that both implants in combination with chlorhexidine were not contaminated with S.aureus bacteria for 2 days under conditions of a high concentration of cells in the suspension. Regulation of bacterial adhesion using biocidal solutions can be a simple and economical strategy to combat the development of infection in the field of surgical intervention. |
| format | Article |
| id | doaj-art-a2cab32e4b31460e9ef04c35f0ecbe8c |
| institution | Matheson Library |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-a2cab32e4b31460e9ef04c35f0ecbe8c2025-08-03T13:04:42ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-016211-12122054Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro)M. V. Kuznetsova0A. A. Parshakov1E. V. Afanasyevskaya2V. A. Samartsev3Perm State Medical University named after Academician E. A. Wagner; Institute of Ecology and Genetics of Microorganisms, Ural Branch of RASPerm State Medical University named after Academician E. A. WagnerPerm State Medical University named after Academician E. A. WagnerPerm State Medical University named after Academician E. A. WagnerThe adhesion of Staphylococcus aureus ATCC® 25923 and the clinical strains of S.aureus, S.epidermidis on monofilament surgical mesh implants - macroporous polyester and microporous polypropylene in combination with biocides was assessed in an in vitro experiment. Staphylococcus cells adhered to the surface of implant fragments without treatment with biocides within a few hours, and there was no significant effect on the adhesion of the structure or chemical composition of the fiber. Short-term exposure of implants to the solutions of amoxiclav (100 μg/ml) and chlorhexidine (0.5%) led to inhibition of bacterial growth and contamination of the surface for at least two days. In the experiment with vancomycin (100 μg/ml), bacterial cells adhered on the surface of the mesh fragments after 24 h, but their amount was significantly lower than in the control group. It was noted that both implants in combination with chlorhexidine were not contaminated with S.aureus bacteria for 2 days under conditions of a high concentration of cells in the suspension. Regulation of bacterial adhesion using biocidal solutions can be a simple and economical strategy to combat the development of infection in the field of surgical intervention.https://www.antibiotics-chemotherapy.ru/jour/article/view/55staphylococcus aureusstaphylococcus epidermidisstaphylococcus aureusstaphylococcus epidermidisbiofilmsmesh implantpolypropylenepolyesterbiocides |
| spellingShingle | M. V. Kuznetsova A. A. Parshakov E. V. Afanasyevskaya V. A. Samartsev Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro) Антибиотики и Химиотерапия staphylococcus aureus staphylococcus epidermidis staphylococcus aureus staphylococcus epidermidis biofilms mesh implant polypropylene polyester biocides |
| title | Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro) |
| title_full | Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro) |
| title_fullStr | Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro) |
| title_full_unstemmed | Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro) |
| title_short | Inhibition of Adhesion of Staphylococcus Bacteria on Mesh Implants in Combination with Biocides (in vitro) |
| title_sort | inhibition of adhesion of staphylococcus bacteria on mesh implants in combination with biocides in vitro |
| topic | staphylococcus aureus staphylococcus epidermidis staphylococcus aureus staphylococcus epidermidis biofilms mesh implant polypropylene polyester biocides |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/55 |
| work_keys_str_mv | AT mvkuznetsova inhibitionofadhesionofstaphylococcusbacteriaonmeshimplantsincombinationwithbiocidesinvitro AT aaparshakov inhibitionofadhesionofstaphylococcusbacteriaonmeshimplantsincombinationwithbiocidesinvitro AT evafanasyevskaya inhibitionofadhesionofstaphylococcusbacteriaonmeshimplantsincombinationwithbiocidesinvitro AT vasamartsev inhibitionofadhesionofstaphylococcusbacteriaonmeshimplantsincombinationwithbiocidesinvitro |