Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPS
This article analyses some literature data and the authors’ developments in the technology of creating of therapeutic depots in the form of films, dispersions of metal oxides and textiles with immobilized biocompatible silver nanoparticles (NPs) in the structure of SiO2, TiO2, cotton, biopolymers...
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Chuiko Institute of Surface Chemistry of NAS of Ukraine
2023-08-01
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| Series: | Хімія, фізика та технологія поверхні |
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| author | A. M. Eremenko I. S. Petrik A. V. Rudenko |
| author_facet | A. M. Eremenko I. S. Petrik A. V. Rudenko |
| author_sort | A. M. Eremenko |
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This article analyses some literature data and the authors’ developments in the technology of creating of therapeutic depots in the form of films, dispersions of metal oxides and textiles with immobilized biocompatible silver nanoparticles (NPs) in the structure of SiO2, TiO2, cotton, biopolymers (alginate, chitosan, lignin, etc.), that have biocidal action, and future trends in this area. We and other researchers have developed methods for the synthesis of photocatalytically active TiO2 and SiO2 films, modified with gold/silver/copper NPs, suitable for medical use. An economical and simple low-temperature methods of manufacturing antimicrobial textiles by photo- or thermal activation and the possibility of their multiple use have been developed. The production of biomedical textiles is recently focused on the widespread use of non-toxic biopolymers, combined with textile. We have obtained compositions based on nanodispersed silica with polysaccharide sodium alginate and silver NPs with pronounced hemostatic and bactericidal properties. Obtaining a hybrid material based on a bactericidal textile combined with a dispersed oxide is promising for additional absorption of toxins and wound cleaning. The creation of such universal multifunctional materials includes their high bactericidal and antiviral multiply use. Hybrid materials based on metal NPs in the structure of carriers of different nature as films and dispersions of biocompatible oxides, biopolymers, textiles have a protection against possible toxic effects of nanoparticles and metal ions, self-cleaning capability, photocatalytic, hemostatic properties, temperature resistance, and other. The development and application of such materials is growing rapidly. So, materials based on Ag/SiO2 dispersions have high antibacterial and antiviral action (single application). Ag/SiO2 films can act as durable antibacterial cover.
There is an enhancement in the antibacterial properties of Ag-TiO2 NPs under visible light irradiation and the photocatalytic effect under UV light (single application in the powder form). Self-cleaning, antimicrobial and UV-protective properties have Ag-TiO2 NPs in textile. Cotton modified with MeNPs demonstrates high efficiency of destruction of bacteria E. coli, K. pneumoniae, E. aerogenes, P. vulgaris, S. aureus, C. albicans, etc., with saving of biocidal activity after 5 cycles of washing. The dynamics of silver ions release from the surface of NPs in the structure of textile upon their contact with water for 72 hours have been studied. The number of irreversibly bound particles in textile structure is sufficient for subsequent use. Modified fabrics are reusable. Composites based on metal NPs in the structure of silica or titania in the presence of biopolymers are effective hemostatic agents with a bactericidal effect. Sodium alginate has a reducing and stabilizing effect on nanoparticles, and silica prevents agglomeration of metal NPs in the resulting composite.
However, it is quite difficult to satisfy the numerous target requirements for biomedical nanomaterials based on metal NPs in the composition of dispersed oxides as well as textiles and/or biopolymers (“all in one”) to obtain a single universal multifunctional material that does not lose its properties during operation. It makes more sense to produce composites for purpose targeted applications, such as bactericidal and antiviral, hydrophobic coatings for laboratory surfaces, package and so on. Researches in this area are in progress. |
| format | Article |
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| institution | Matheson Library |
| issn | 2079-1704 2518-1238 |
| language | English |
| publishDate | 2023-08-01 |
| publisher | Chuiko Institute of Surface Chemistry of NAS of Ukraine |
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| series | Хімія, фізика та технологія поверхні |
| spelling | doaj-art-a2a1fb9a33da4d6a8e43317d9124e8822025-07-22T18:24:20ZengChuiko Institute of Surface Chemistry of NAS of UkraineХімія, фізика та технологія поверхні2079-17042518-12382023-08-0114310.15407/hftp14.03.300Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPSA. M. Eremenko0I. S. Petrik1A. V. Rudenko2Chuiko Institute of Surface Chemistry of National Academy of Sciences of UkraineChuiko Institute of Surface Chemistry of National Academy of Sciences of UkraineDU “Institute of Urology named after Academician O.F. Vozianov” of National Academy of Medical Sciences of Ukraine This article analyses some literature data and the authors’ developments in the technology of creating of therapeutic depots in the form of films, dispersions of metal oxides and textiles with immobilized biocompatible silver nanoparticles (NPs) in the structure of SiO2, TiO2, cotton, biopolymers (alginate, chitosan, lignin, etc.), that have biocidal action, and future trends in this area. We and other researchers have developed methods for the synthesis of photocatalytically active TiO2 and SiO2 films, modified with gold/silver/copper NPs, suitable for medical use. An economical and simple low-temperature methods of manufacturing antimicrobial textiles by photo- or thermal activation and the possibility of their multiple use have been developed. The production of biomedical textiles is recently focused on the widespread use of non-toxic biopolymers, combined with textile. We have obtained compositions based on nanodispersed silica with polysaccharide sodium alginate and silver NPs with pronounced hemostatic and bactericidal properties. Obtaining a hybrid material based on a bactericidal textile combined with a dispersed oxide is promising for additional absorption of toxins and wound cleaning. The creation of such universal multifunctional materials includes their high bactericidal and antiviral multiply use. Hybrid materials based on metal NPs in the structure of carriers of different nature as films and dispersions of biocompatible oxides, biopolymers, textiles have a protection against possible toxic effects of nanoparticles and metal ions, self-cleaning capability, photocatalytic, hemostatic properties, temperature resistance, and other. The development and application of such materials is growing rapidly. So, materials based on Ag/SiO2 dispersions have high antibacterial and antiviral action (single application). Ag/SiO2 films can act as durable antibacterial cover. There is an enhancement in the antibacterial properties of Ag-TiO2 NPs under visible light irradiation and the photocatalytic effect under UV light (single application in the powder form). Self-cleaning, antimicrobial and UV-protective properties have Ag-TiO2 NPs in textile. Cotton modified with MeNPs demonstrates high efficiency of destruction of bacteria E. coli, K. pneumoniae, E. aerogenes, P. vulgaris, S. aureus, C. albicans, etc., with saving of biocidal activity after 5 cycles of washing. The dynamics of silver ions release from the surface of NPs in the structure of textile upon their contact with water for 72 hours have been studied. The number of irreversibly bound particles in textile structure is sufficient for subsequent use. Modified fabrics are reusable. Composites based on metal NPs in the structure of silica or titania in the presence of biopolymers are effective hemostatic agents with a bactericidal effect. Sodium alginate has a reducing and stabilizing effect on nanoparticles, and silica prevents agglomeration of metal NPs in the resulting composite. However, it is quite difficult to satisfy the numerous target requirements for biomedical nanomaterials based on metal NPs in the composition of dispersed oxides as well as textiles and/or biopolymers (“all in one”) to obtain a single universal multifunctional material that does not lose its properties during operation. It makes more sense to produce composites for purpose targeted applications, such as bactericidal and antiviral, hydrophobic coatings for laboratory surfaces, package and so on. Researches in this area are in progress.https://cpts.com.ua/index.php/cpts/article/view/681metal nanoparticles (NPs)metal oxide nanoparticles (MeONPs)biopolymerscolloidsSiO2 filmsTiO2 nanoparticles |
| spellingShingle | A. M. Eremenko I. S. Petrik A. V. Rudenko Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPS Хімія, фізика та технологія поверхні metal nanoparticles (NPs) metal oxide nanoparticles (MeONPs) biopolymers colloids SiO2 films TiO2 nanoparticles |
| title | Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPS |
| title_full | Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPS |
| title_fullStr | Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPS |
| title_full_unstemmed | Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPS |
| title_short | Targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal NPS |
| title_sort | targeted requirements for biomedical nanomaterials based on dispersed oxides and textiles modified with metal nps |
| topic | metal nanoparticles (NPs) metal oxide nanoparticles (MeONPs) biopolymers colloids SiO2 films TiO2 nanoparticles |
| url | https://cpts.com.ua/index.php/cpts/article/view/681 |
| work_keys_str_mv | AT ameremenko targetedrequirementsforbiomedicalnanomaterialsbasedondispersedoxidesandtextilesmodifiedwithmetalnps AT ispetrik targetedrequirementsforbiomedicalnanomaterialsbasedondispersedoxidesandtextilesmodifiedwithmetalnps AT avrudenko targetedrequirementsforbiomedicalnanomaterialsbasedondispersedoxidesandtextilesmodifiedwithmetalnps |