Pharmacokinetics, Safety, and Tolerability of (R)-Ketamine Hydrochloride Injection, a Novel Rapid-Acting Antidepressant, in Healthy Chinese Subjects

Pharmacokinetics, Safety, and Tolerability of (R)-Ketamine Hydrochloride Injection, a Novel Rapid-Acting Antidepressant, in Healthy Chinese Subjects

<b>Objectives</b>: (R)-ketamine hydrochloride injection is a novel, rapid-acting antidepressant for the treatment of treatment-resistant depression. The aim of this study was to assess the pharmacokinetics, safety, and tolerability of (R)-ketamine hydrochloride injection in healthy Chine...

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Autori principali: Rui Wang, Yuqian Yang, Tong Zhou, Bingjie Zou, Li Ding
Natura: Articolo
Lingua:inglese
Pubblicazione: MDPI AG 2025-07-01
Serie:Pharmaceuticals
Soggetti:
(R)-ketamine
(R)-norketamine
treatment-resistant depression
N-methyl-D-aspartate receptor antagonist
pharmacokinetics
safety
Accesso online:https://www.mdpi.com/1424-8247/18/7/1079
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