C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

Abstract Nasopharyngeal carcinoma (NPC) is one of the common head and neck cancers in Southern China and Southeast Asia. Although current studies have adequately characterized the tumor microenvironment (TME) of NPC, little attention has been paid to how cell‐cell interactions within the TME promote...

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Bibliographic Details
Main Authors: Yunzhi Liu, Cuicui Huang, Min Luo, Wenfu Lu, Baifeng Zhang, Lu Bai, Shuyue Zheng, Yanan Tan, Shanshan Li, Huali Wang, Lanqi Gong, Xinyuan Guan
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
C1q
DNA hypermethylation
nasopharyngeal carcinoma
PI3K/AKT signaling
tumor‐associated macrophage
Online Access:https://doi.org/10.1002/advs.202503434
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