Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19
Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-Acute Sequelae of COVID-19 (PASC) often have neurocognitive complaints that involve memory and concentration problems and difficulties paying attention. Other neurocognitive domains such as hypersensitivity to noise a...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
|
| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1612548/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839628728861196288 |
|---|---|
| author | Ariadna Sandoval Mingqi Li Leonard A. Jason |
| author_facet | Ariadna Sandoval Mingqi Li Leonard A. Jason |
| author_sort | Ariadna Sandoval |
| collection | DOAJ |
| description | Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-Acute Sequelae of COVID-19 (PASC) often have neurocognitive complaints that involve memory and concentration problems and difficulties paying attention. Other neurocognitive domains such as hypersensitivity to noise and light have rarely been included as aspects of neurocognitive impairment for these post-viral conditions. The current study evaluated a more extensive list of neurocognitive items for a group of 2,313 patients with ME/CFS and 299 patients with PASC. Exploratory factor analyses found two factors for each patient group, one involving classic memory and concentration symptoms and the other involving sensory overload phenomena. The findings suggest that researchers might consider expanding the types of self-report neurocognitive symptoms among patients with these post-viral illnesses. |
| format | Article |
| id | doaj-art-a1a6b44d1b8842cca7ad6206c995412e |
| institution | Matheson Library |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-a1a6b44d1b8842cca7ad6206c995412e2025-07-15T11:59:56ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-07-011610.3389/fneur.2025.16125481612548Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19Ariadna SandovalMingqi LiLeonard A. JasonPatients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-Acute Sequelae of COVID-19 (PASC) often have neurocognitive complaints that involve memory and concentration problems and difficulties paying attention. Other neurocognitive domains such as hypersensitivity to noise and light have rarely been included as aspects of neurocognitive impairment for these post-viral conditions. The current study evaluated a more extensive list of neurocognitive items for a group of 2,313 patients with ME/CFS and 299 patients with PASC. Exploratory factor analyses found two factors for each patient group, one involving classic memory and concentration symptoms and the other involving sensory overload phenomena. The findings suggest that researchers might consider expanding the types of self-report neurocognitive symptoms among patients with these post-viral illnesses.https://www.frontiersin.org/articles/10.3389/fneur.2025.1612548/fullneurocognitivehypersensitivitysalience networkmyalgic encephalomyelitisPASC/long COVIDfactor analyses |
| spellingShingle | Ariadna Sandoval Mingqi Li Leonard A. Jason Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19 Frontiers in Neurology neurocognitive hypersensitivity salience network myalgic encephalomyelitis PASC/long COVID factor analyses |
| title | Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19 |
| title_full | Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19 |
| title_fullStr | Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19 |
| title_full_unstemmed | Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19 |
| title_short | Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19 |
| title_sort | two neurocognitive domains identified for patients with myalgic encephalomyelitis chronic fatigue syndrome and post acute sequelae of covid 19 |
| topic | neurocognitive hypersensitivity salience network myalgic encephalomyelitis PASC/long COVID factor analyses |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1612548/full |
| work_keys_str_mv | AT ariadnasandoval twoneurocognitivedomainsidentifiedforpatientswithmyalgicencephalomyelitischronicfatiguesyndromeandpostacutesequelaeofcovid19 AT mingqili twoneurocognitivedomainsidentifiedforpatientswithmyalgicencephalomyelitischronicfatiguesyndromeandpostacutesequelaeofcovid19 AT leonardajason twoneurocognitivedomainsidentifiedforpatientswithmyalgicencephalomyelitischronicfatiguesyndromeandpostacutesequelaeofcovid19 |