Langerhans cells drive Tfh and B cell responses independent of canonical cytokine signals

Langerhans cells drive Tfh and B cell responses independent of canonical cytokine signals

Dendritic cells (DCs) are key regulators of adaptive immunity, guiding T helper (Th) cell differentiation through antigen presentation, co-stimulation, and cytokine production. However, in steady-state conditions, certain DC subsets, such as Langerhans cells (LCs), induce T follicular helper (Tfh) c...

Full description

Saved in:
Bibliographic Details
Main Authors: Aurélie Bouteau, Zhen Qin, Sandra Zurawski, Gerard Zurawski, Botond Z. Igyártó
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
Langerhans cell
steady - state
adaptive immunity
dendritic cell
TFH
B cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1611812/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items